| Cat. No. |
Product Name |
Information |
| PC-21002 |
FDW028
FUT8 inhibitor
|
FDW028 is a potent and highly selective small-molecule inhibitor of fucosyltransferase 8 (FUT8) with binding KD value of 5.486 uM, displays no affinity against other FUTs, shows potent anti-CRC activities. |
| PC-20988 |
Tax-1-hDLG1 inhibitor 3
Tax-1-hDLG1 inhibitor
|
Tax-1-hDLG1 inhibitor 3 (iTax/PDZ-01) is a small molecule inhibitor of Tax-1-hDLG1 interaction with EC50 of 11.5 uM, blocks HTLV-1 cell to cell transmission and viral replication. |
| PC-20977 |
ZINC549719643
AmpC β-lactamase inhibitor
|
ZINC549719643 is a highly potent inhibitor of AmpC β-lactamase with IC50 of 77 nM. |
| PC-20955 |
DHCR24 inhibitor SH42
DHCR24 inhibitor
|
DHCR24 inhibitor SH42 is a potent, selective, non-toxic delta 24-dehydrocholesterol reductase (DHCR24, Seladin-1) inhibitor, inhibits overall cholesterol biosynthesis in HL-60 cells with IC50 of 4.2 nM. |
| PC-20946 |
PSF-RNA inhibitor C-65
PSF-RNA inhibitor
|
PSF-RNA inhibitor C-65 is a small molecule inhibitor of RNA-binding protein PSF and its target RNA with IC50 of 0.02 uM in pull-down assays. |
| PC-20936 |
NV848
FTSJ1 inhibitor
|
NV848 is a small molecule inhibitor of tRNA-specific 2′-O-methyltransferase (FTSJ1), exerts readthrough activity in vitro and in vivo. |
| PC-20933 |
GSK898
KMO inhibitor
|
GSK898 is a potent, highly selective kynurenine monooxygenase (KMO) inhibitor with pIC50 of 8.8. |
| PC-20909 |
GPR56 agonist 36
GPR56 agonist
|
GPR56 agonist 36 is a potent selective agonist of adhesion GPCR ADGRG1/GPR56 with EC50 of 2.95 uM. |
| PC-20902 |
Luvadaxistat
DAAO inhibitor
|
Luvadaxistat (TAK-831, NBI-1065844) is a highly potent, selective D-amino acid oxidase (DAAO) inhibitor with IC50 of 14 nM against human recombinant DAAO enzyme. |
| PC-20890 |
Lalistat-1
LAL inhibitor
|
Lalistat 1 (Lalistat 1) is a potent and selective lysosomal acid lipase (LAL) inhibitor with IC50 of 68 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase. |
| PC-20889 |
Lalistat-2
LAL inhibitor
|
Lalistat-2 (L-stat, Lalistat 2) is a specific inhibitor of lysosomal acid lipase (LAL) with IC50 of 152 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase. |
| PC-20847 |
C902
LIN28 inhibitor
|
C902 is a small-molecule inhibitor targeting LIN28-let-7 interaction, shows dose-dependent inhibition in an EMSA validation assay with IC50 of 5 uM. |
