Chemical Structure : AGI-41998
CAS No.: 2377492-26-5
Catalog No.: PC-21474Not For Human Use, Lab Use Only.
AGI-41998 is a potent selective and brain-penetrant methionine adenosyltransferase 2A (MAT2A) inhibitor with IC50 of 22 nM.
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AGI-41998 is a potent selective and brain-penetrant methionine adenosyltransferase 2A (MAT2A) inhibitor with IC50 of 22 nM.
M.Wt | 505.30 | |
Formula | C22H16BrF3N4O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-[(2,2,2-trifluoroethyl)amino]- |
1. Mingzong Li, et al. J Med Chem. 2022 Mar 24;65(6):4600-4615.
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