| Cat. No. |
Product Name |
Information |
| PC-21097 |
PSB-KK1415
GPR18 agonist
|
PSB-KK1415 is a selective GPR18 agonist with EC50 of 19.1 nM (hGPR18) in β-arrestin recruitment assays, shows no activity against GPR55. |
| PC-21076 |
JSD26
SCoR2 inhibitor
|
JSD26 is a selective S-nitroso-coenzyme A reductase 2 (SCoR2; AKR1A1) inhibitor with Ki of 93 nM, 10-fold selectivity over AKR1B1. |
| PC-21070 |
NP-G2-044
Fascin inhibitor
|
NP‐G2‐044 is a small molecule inhibitor of actin-bundling protein Fascin-1 (Fscn1), inhibits fascin-mediated actin bundling with IC50 of 0.2 uM. |
| PC-21054 |
SOFTI
SPINDLY inhibitor
|
SOFTI is a small molecule inhibitor of O-fucosyltransferase SPINDLY (SPY) with IC50 of 13.32 uM, binds to the GDP-fucose-binding pocket of SPY and competitively inhibits GDP-fucose binding. |
| PC-21021 |
PF-07208254
BDK inhibitor
|
PF-07208254 (PF 07208254) is a potent, allosteric branched-chain ketoacid dehydrogenase kinase (BDK, BCKDK) inhibitor with in vitro IC50 of 110 nM and Ki of 54 nM. |
| PC-21020 |
PF-07247685
BDK inhibitor
|
PF-07247685 (PF-07247685) is a potent, allosteric branched-chain ketoacid dehydrogenase kinase (BDK) inhibitor with in vitro IC50 of 0.86 nM, and SPR Kd of 0.68 nM. |
| PC-21015 |
YB-537
Quinone reductase 2 inhibitor
|
YB-537 (YB537) is a potent, highly specific quinone reductase 2 (QR2) inhibitor with IC50 of 3 nM, shows no activity against QR1 (IC50>10 uM). |
| PC-21002 |
FDW028
FUT8 inhibitor
|
FDW028 is a potent and highly selective small-molecule inhibitor of fucosyltransferase 8 (FUT8) with binding KD value of 5.486 uM, displays no affinity against other FUTs, shows potent anti-CRC activities. |
| PC-20977 |
ZINC549719643
AmpC β-lactamase inhibitor
|
ZINC549719643 is a highly potent inhibitor of AmpC β-lactamase with IC50 of 77 nM. |
| PC-20955 |
DHCR24 inhibitor SH42
DHCR24 inhibitor
|
DHCR24 inhibitor SH42 is a potent, selective, non-toxic delta 24-dehydrocholesterol reductase (DHCR24, Seladin-1) inhibitor, inhibits overall cholesterol biosynthesis in HL-60 cells with IC50 of 4.2 nM. |
| PC-20946 |
PSF-RNA inhibitor C-65
PSF-RNA inhibitor
|
PSF-RNA inhibitor C-65 is a small molecule inhibitor of RNA-binding protein PSF and its target RNA with IC50 of 0.02 uM in pull-down assays. |
| PC-20847 |
C902
LIN28 inhibitor
|
C902 is a small-molecule inhibitor targeting LIN28-let-7 interaction, shows dose-dependent inhibition in an EMSA validation assay with IC50 of 5 uM. |
