ST80 | OTUD4-CD73 inhibitor | Probechem Biochemicals

Chemical Structure : ST80

ST80 (OTUD4-CD73 inhibitor ST80)

Catalog No.: PC-22049Not For Human Use, Lab Use Only.

ST-80 is a specific small molecule inhibitor of interaction between CD73 and OTUD4, specifically disrupts proteolytic interaction between CD73 and OTUD4, leading to reinvigoration of cytotoxic CD8+ T cell activities.

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Biological Activity

ST-80 is a specific small molecule inhibitor of interaction between CD73 and OTUD4, specifically disrupts proteolytic interaction between CD73 and OTUD4, leading to reinvigoration of cytotoxic CD8+ T cell activities.

Physicochemical Properties

M.Wt	457.51
Formula	C26H24FN5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(7-(4-fluorophenyl)-5-(p-tolyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione

References

1. Zhu Y, et al. J Clin Invest. 2024 Mar 26:e176390.

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ST80 (OTUD4-CD73 inhibitor ST80)

Biological Activity

Physicochemical Properties

References

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