| Cat. No. |
Product Name |
Information |
| PC-42293 |
EC330
LIF inhibitor
|
EC330 (EC-330, EC 330) is a first-in-class, orally bioavailable LIF (leukemia inhibitory factor, LIFR) inhibitor. |
| PC-45088 |
SP-420
Iron chelating agent
|
Petadeferitrin (SP-420) is a desferrithiocin analogue and iron chelating agent that has iron-clearing efficiency with ICE value of 26.7, SP-420 is more potent than desferrithiocin. |
| PC-45513 |
HQ-415
Metal chelator, TDP-43 modulator
|
HQ-415 is a derivative of 8-hydroxyquinoline that has selectivity for rescuing the distinct toxicities caused by the expression of TDP-43 with EC50 of 15 uM, α-synuclein or polyglutamine proteins. |
| PC-45271 |
Pramiracetam
Cognitive activator
|
Pramiracetam (CI-879) is a central nervous system stimulant and nootropic agent and PREP (prolyl endopeptidase) inhibitor, shows cognition-restoring and neuroprotective properties. |
| PC-42072 |
BAPTA
Mg2+ chelator
|
BAPTA is a cell-permeant, calcium-specific chelator with high selectivity over Mg2+. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-28509 |
Edaravoside
Free radical scavenger
|
Edaravoside is a free radical scavenger investigated for neuroprotective effects in ischemic stroke. |
| PC-28503 |
CD38 inhibitor 16
CD38 inhibitor
|
CD38 inhibitor 16 is a potent, selective and brain-penetrant CD38 inhibitor with IC50 of 2.71 nM and 1.94 nM for mCD38 and hCD37 respectively. |
| PC-28493 |
Compound 9787
RpS5 modulator
|
Compound 9787 is a specific small molecule targeting 30S ribosomal protein S5 (RpS5), enhances translational fidelity at concentrations does not impact the overall rate of protein synthesis, reverses rifampicin tolerance. |
| PC-28461 |
LCL521 dihydrochloride
Acid ceramidase inhibitor
|
LCL521 dihydrochloride (1,3-di-DMG-B13) is a small molecular inhibitor of acid ceramidase (ACDase), a lysosomotropic inhibitor with anticancer activity. |
