K784-8160 | TIPE3 inhibitor | Probechem Biochemicals

Chemical Structure : K784-8160

K784-8160 (ZINC000006756082)

Catalog No.: PC-22325Not For Human Use, Lab Use Only.

K784-8160 is a small molecule inhibitor of tumor necrosis factor-α-induced protein 8-like 3 (TNFAIP8L3, TIPE3), exhibits potent anti-tumor activities.

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Biological Activity

K784-8160 is a small molecule inhibitor of tumor necrosis factor-α-induced protein 8-like 3 (TNFAIP8L3, TIPE3), exhibits potent anti-tumor activities.
K784-8160 induces a dose-dependent decrease in the viability of HT-29 cells and LoVo cells, with IC50 values of 4.94 μM and 26.35 μM, respectively.

Physicochemical Properties

M.Wt	400.50
Formula	C23H20N4OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-2-(1-benzyl-2-oxoindolin-3-ylidene)-N-(o-tolyl)hydrazine-1-carbothioamide

References

1. Chen X, et al. Cells. 2024 Apr 30;13(9):771.

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K784-8160 (ZINC000006756082)

Biological Activity

Physicochemical Properties

References

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