| Cat. No. |
Product Name |
Information |
| PC-61689 |
Fhit-IN-15
Fhit inhibitor
|
Fhit-IN-15 is a potent, competitive, reversible inhibitor of the enzymatic activity of tumor suppressor Fhit with IC50 of 49 nM, shows cytotoxicity in HEK293T cells. |
| PC-61683 |
Juglone
|
Juglone (5-HN) is a plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities. |
| PC-61677 |
ATN-224
SOD1 inhibitor
|
ATN-224 (Choline tetrathiomolybdate, WTX-101) is a specific, high-affinity copper binder that inhibits CuZn superoxide dismutase 1 (SOD1) with IC50 of 0.33 uM against purified bovine SOD1, leading to antiangiogenic and antitumour effects. |
| PC-61674 |
SBI-993
MondoA inhibitor
|
SBI-993 is an analog of SBI-477 that shows improved potency and suitable pharmacokinetic properties for in vivo bioavailability. |
| PC-61673 |
SBI-477
MondoA inhibitor
|
SBI-477 is a chemical probe that coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes with EC50 of 100 nM and 1 uM, respectively. |
| PC-61554 |
ML154
NPSR antagonist
|
ML154 (NCGC00185684) is a potent, selective, brain penetrant NPSR (Neuropeptide S receptor, GPR154) antagonist with IC50 of 22.1 nM and 36.5 nM in Ca2+ assay and cAMP assay, respectively. |
| PC-61519 |
NPD926
ROS inducer
|
NPD926 is a small molecule ROS inducer that induces rapid cell death in cancer cells, induces reactive oxygen species via cellular glutathione depletion. |
| PC-61485 |
VJ115
ENOX1 inhibitor
|
VJ115 (VJ-115) is a small molecule inhibitor of NADH oxidase ENOX1 with IC50 of 10 uM, increases intracellular NADH in endothelial cells and inhibits endothelial cell tubule formation. |
| PC-61473 |
BI 1467335
VAP-1 inhibitor
|
BI 1467335 (PXS-4728A, PXS-4728) is a potent, selective, orally active SSAO/VAP-1 (AOC3) inhibitor with IC50 of 5 nM. |
| PC-61472 |
PXS-4681A
VAP-1 inhibitor
|
PXS-4681A is a potent, selective, and irreversible inhibitor of semicarbazide-sensitive amine oxidase (SSAO, VAP-1) with Ki of 37 nM, IC50 of <10 nM. |
| PC-61463 |
VPC-18005
ERG antagonist
|
VPC-18005 (VPC18005) is a novel small molecule ERG (ETS-related gene) antagonist that inhibits ERG-induced transcription and interacts directly with the ERG-ETS domain, disrupts the ERG binding to DNA (Kd=250 uM). |
| PC-61429 |
Lucerastat
GCS inhibitor
|
Lucerastat (NB-DGJ, ACT-434964) is a galactose analogue that is an UDP-glucose ceramide glucosyltransferase (UGCG/GCS) inhibitor (IC50=41.4 uM). |
