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Cat. No. Product Name Information
PC-61262

TB-03

Grb2 SH2 inhibitor

TB-03 is a small molecule Grb2 SH2 domain binding antagonist that synergistically enhances inhibition of K562 leukemia cell proliferation by imatinib (CI=0.774).
PC-61245

DC_AC50

DC_AC50 (DCAC50) is a small molecule that inhibits the human copper chaperones Atox1 and CCS (Kd=6.8 and 8.2 uM), blocks copper trafficking and significantly attenuates cancer cell proliferation.
PC-61244

STOML3 inhibitor OB-1

STOML3 inhibitor OB-1 is a small-molecule inhibitor of STOML3 oligomerization that reverses pathological mechanical hypersensitivity in vivo.
PC-61243

r(GGGGCC)n binder 1a

A bioactive, specific small molecule that targets RNA of the expanded repeat (r(GGGGCC)exp) with Kd of 9.7 uM.
PC-61242

UNC-3230

PIP5K1C inhibitor

UNC-3230 (UNC3230) is a selective, small molecule inhibitor of PIP5K1C with IC50 of 41 nM, does not ihibits other lipid kinases including PI3Ks.
PC-61241

SPRi3

SPRi3 (SPR inhibitor 3) is a small molecule inhibitor of sepiapterin reductase (SPR) with IC50 of 74 nM in cell-free assays, efficiently reduces biopterin levels with IC50 of 5.2 uM.
PC-61236

AGI-1067

AGI-1067 (Succinobucol) is a potent inhibitor of TNF-α-inducible expression of VCAM-1, MCP-1 and E-selectin (IC50=6,10 and 25 uM) with concurrent antioxidant and lipid-modulating properties.
PC-61225

DFPM

Abscisic acid inhibitor

DFPM is a small molecule that rapidly downregulates abscisic acid (ABA)-dependent gene expression (IC50=3 and 1.5 uM for RD29B and RAB18 promoters), also inhibits ABA-induced stomatal closure.
PC-61214

Pyrimidinone 8

DMT1 inhibitor

Pyrimidinone 8 is a novel allosteric, non-competitive divalent metal transporter-1 (SLC11A2/DMT1) inhibitor with Ki of 20 uM.
PC-61208

Ferristatin II

Iron transport inhibitor

Ferristatin II (NSC 8679, NSC8679, Chlorazol Black) is a small molecule iron transport inhibitor that promotes degradation of transferrin receptor-1 in vitro and in vivo, through a nystatin-sensitive lipid raft pathway.
PC-61207

NSC 306711

Iron transport inhibitor

NSC 306711 (Ferristatin, NSC306711) is a small-molecule iron transport inhibitor that promotes degradation of the transferrin receptor independent of clathrin and dynamin, is sensitive to the cholesterol-depleting agents filipin and nystatin.
PC-70268

Shz-1

Nkx2.5 inducer

Shz-1 is a small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells.

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