| Cat. No. |
Product Name |
Information |
| PC-22643 |
TAK-683 acetate
KISS1R agonist
|
TAK-683 acetate is a potent and full KISS1R (metastin receptor) agonist and kisspeptin analogue with IC50 of 3 pM in radioimmunoassay. |
| PC-22642 |
TAK-448 acetate
KISS1R agonist
|
TAK-448 (MVT-602) acetate is a potent and full KISS1R (metastin receptor) agonist and kisspeptin analogue with IC50 of 3 pM in radioimmunoassay. |
| PC-22640 |
(S)-PHA533533
Ube3a unsilencer
|
(S)-PHA533533 is a potent, small molecule unsilencer of paternal UBE3A in mouse primary neurons with EC50 of 0.54 uM, Emax=80%, effectively downregulates Ube3a-ATS/UBE3A ATS and epigenetically unsilences paternal Ube3a/UBE3A in both mouse and human neuron. |
| PC-22636 |
Delphinidin chloride
Hyaluronidase inhibitor
|
Delphinidin chloride is a natural plant compound found in fruits and vegetables, a potent hyaluronidase inhibitor, increases high molecular weight hyaluronic acid (HMW-HA) and inhibits cancer metastasis. |
| PC-22628 |
GGTI-2154 hydrochloride
GGTase I inhibitor
|
GGTI-2154 hydrochloride is a potent, selective inhibitor geranylgeranyltransferase I (GGTase I) with IC50 f 21 nM, >250-fold selective over FTase. |
| PC-22627 |
GGTI-2154
GGTase I inhibitor
|
GGTI-2154 is a potent, selective inhibitor geranylgeranyltransferase I (GGTase I) with IC50 f 21 nM, >250-fold selective over FTase. |
| PC-22615 |
2-BDBPQD
α-glucosidase inhibitor
|
2-BDBPQD is a potent anti-diabetic agent and inhibitor of carbohydrate-degrading enzyme α-glucosidase with IC50 of 63.7 uM, moderately reduces cholesterol and LDL levels, exhibits superior efficacy in reducing glucose levels compared to acarbose. |
| PC-22607 |
Orpinolide
OSBP inhibitor
|
Orpinolide is a synthetic withanolide analog with potent antileukemic properties, directly targets oxysterol-binding protein OSBP, disrupts Golgi homeostasis via a mechanism that requires active phosphatidylinositol 4-phosphate (PtdIns4P, PI4P) signaling at ER-Golgi membrane interface. |
| PC-22606 |
SABRAC
Acid ceramidase inhibitor
|
SABRAC is a highly potent, irreversible inhibitor of acid ceramidase with Ki of 29.7 nM, induces apoptosis and provides a benefit in mice survival in IDH1 mut oligodendroglioma. |
| PC-22604 |
Oxybipin-2
OSBP inhibitor
|
Oxybipin-2 is a potent and selective inhibitor of oxysterol-binding protein (OSBP), inhibits OSBP–22-NBD-Chol interaction with IC50 of 13 nM, impair retrograde trafficking. |
| PC-22593 |
UNC10245380
CIB1 inhibitor
|
UNC10245380 (UNC5380) is a small molecule ligand/inhibitor of Calcium and Integrin Binding protein 1 (CIB1) with IC50 of 8.0 uM in TR-FRET displacement assay, selectively kills CIB1 depletion-sensitive TNBC cells. |
| PC-22571 |
TMLB-C16
B3GAT3 inhibitor
|
TMLB-C16 is a potent beta-1,3-glucuronosyltransferase (B3GAT3) inhibitor with KD of 3.96 uM, suppresses proliferation and migration in HCC cells. |
