| Cat. No. |
Product Name |
Information |
| PC-22430 |
LW-216
TrxR1 inhibitor
|
LW-216 is a novel specific small molecule thioredoxin reductase 1 (TrxR1, TXNRD1) inhibitor directly binds TrxR1 (KD of 8.8 uM in MST assays) and persistently promotes TrxR1 ubiquitination, inhibits TrxR1 expression. |
| PC-22416 |
UCF-101
Omi/HtrA2 inhibitor
|
UCF-101 is a specific inhibitor for the pro-apoptotic protease Omi/HtrA2 with IC50 of 9.5 uM, displays high selectivity over other serine proteases. |
| PC-22408 |
DUPA
Drug delivery ligand
|
DUPA is a small molecule delivery ligand with specificity for prostate-specific membrane antigen (PSMA), commonly used for selectively delivery cytotoxic agents to prostate cancer cells. |
| PC-22397 |
UNC9750
IPMK inhibitor
|
UNC9750 is a potent selective inhibitor of inositol phosphate multikinase (IPMK) with IC50 of 31.6 nM, inhibits human glioblastoma cell growth and selectively decreases cellular InsP5 abundance. |
| PC-22384 |
ML281
STK33 inhibitor
|
ML281 is a potent, selective inhibitor of serine/threonine kinase STK33 with IC50 of 14 nM, >500-fold selective over PKA and AurB. |
| PC-22376 |
18:0 PEG2000 PE
|
18:0 PEG2000 PE is a PEG-modified phospholipid conjugate used in liposome formation of sterically stabilized liposomes with low reticuloendothelial system uptake and increased circulation duration to target cells. |
| PC-22368 |
7-alpha-hydroxycholesterol
TCR inhibitor
|
7alpha-hydroxycholesterol (7a-HC) is the 7alpha-hydroxy derivative of cholesterol, is a potent inhibitor of TCR signaling and promotes membrane binding of CD3ε cytoplasmic domain. |
| PC-22367 |
SHP1705
Cryptochrome stabilizer
|
SHP1705 is a small molecule cryptochrome (CRY) modulator and stabilizer, represses the expression of DBP, CRY1, and PER1, reduces glucose intolerance in obese, insulin-resistant mice. |
| PC-22352 |
Rotenone
Complex I inhibitor
|
Rotenone is a mitochondrial electron transport chain complex I inhibitor, induces apoptosis through enhancing mitochondrial reactive oxygen species production. |
| PC-22351 |
DPPC
|
DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes, DPPC is the main lipid component of pulmonary surfactant. |
| PC-22340 |
QDPR inhibitor 9b
QDPR inhibitor
|
QDPR inhibitor 9b is a small molecule inhibitor of quinonoid dihydropteridine reductase (QDPR) with IC50 of 0.72 uM. |
| PC-22338 |
STL427944
FOXM1 inhibitor
|
STL427944 is a small molecule inhibitor of forkhead box protein M1 (FOXM1), selectively suppresses FOXM1 by inducing the relocalization of nuclear FOXM1 protein to the cytoplasm and promoting its subsequent degradation by autophagosomes. |
