| Cat. No. |
Product Name |
Information |
| PC-24651 |
LC-20W
hCES2A inhibitor
|
LC-20W is potent, reversible human carboxylesterase 2A (hCES2A) inhibitor with IC50 of 1.6 nM. |
| PC-24650 |
Cucurbitacin B
IGF2BP1 inhibitor
|
Cucurbitacin B (CuB) is a potent but toxic anticancer natural product, an irreversible covalent inhibitor of IGF2BP1 and forms a covalent bond with cysteine 253 of the IGF2BP1 KH 1-2 domain (KD=66.8 nM). |
| PC-24648 |
DB2115 tertahydrochloride
PU.1 inhibitor
|
DB2115 tertahydrochloride is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 1.0 nM. |
| PC-24627 |
HSD17B13 inhibitor 32
HSD17B13 inhibitor
|
HSD17B13 inhibitor 32 is a highly potent, selective and liver-targeting HSD17B13 inhibitor with IC50 of 2.5 nM. |
| PC-24621 |
Fis1 inhibitor SP11
Fis1 inhibitor
|
SP11 is a potent inhibitor of activated Fis1 (mitochondrial fission protein 1), covalently binds specifically to Cys41 of activated Fis1, inhibits CPM fluorescence of Thr34Asp Fis1 with IC50 of 9.4 uM. |
| PC-24615 |
Digitonin
Detergent agent
|
Digitonin is a natural glycoside detergent glycoside obtained from Digitalis purpurea, can increase cell permeability by binding to cholesterol molecules and reduce tumor growth. |
| PC-24605 |
Concanavalin A
Liver injury inducer
|
Concanavalin A is a Ca2+/Mn2+-dependent and mannose/glucose-binding plant lectin, can induce programmed cell death and acute liver injury. |
| PC-24596 |
SALL4 inhibitor SH6
SALL4 degrader
|
SALL4 inhibitor SH6 is a small molecule inhibitor of transcription factor SALL4 ZFC4 domain, selectively targets SALL4-expressing cancer cells (EC50=0.5 uM, SNU398 cells), degrades SALL4 protein through the CUL4A/CRBN pathway. |
| PC-24578 |
TrpGc
HINT1 inhibitor
|
TrpGc (Tryptamine guanosine carbamate) is a pharmacologically active histidine triad nucleotide-binding protein (HINT1) inhibitor with Kd of 3.65 uM, IC50 of 9.1 uM. |
| PC-24577 |
MBLAC2 inhibitor KV-79
MBLAC2 inhibitor
|
MBLAC2 inhibitor KV-79 is a potent, specific inhibitor of the metalloenzyme MBLAC2 (Metallo-Beta-Lactamase Domain Containing 2) with EC50 of 24 nM, >60 fold selectivity over HDAC6. |
| PC-24576 |
MBLAC2 inhibitor KV-65
MBLAC2 inhibitor
|
MBLAC2 inhibitor KV-65 is a potent, specific inhibitor of the metalloenzyme MBLAC2 (Metallo-Beta-Lactamase Domain Containing 2) with EC50 of 37 nM, 64-fold selectivity over HDAC6. |
| PC-24553 |
FGH10019
SREBP inhibitor
|
FGH10019 is a specific small molecule inhibitor of sterol regulatory element-binding protein (SREBP) with IC50 of 0.7 uM in SREBP-responsive reporter gene assays. |
