| Cat. No. |
Product Name |
Information |
| PC-21176 |
GPR54 antagonist 9l
GPR54 inhibitor
|
GPR54 antagonist 9l is a potent, selective, small molecule antagonist of GPR54 with IC50 of 3.7 nM (human GPR54) in receptor binding assays. |
| PC-21175 |
GPR54 antagonist 15a
GPR54 inhibitor
|
GPR54 antagonist 15a is a potent, selective, small molecule antagonist of GPR54 with IC50 of 3.6/15 nM (human/rat GPR54) in receptor binding assays. |
| PC-21174 |
KISS1R antagonist P234
GPR54 inhibitor
|
KISS1R antagonist P234 (GPR54 antagonist P234, Peptide P234) is a potent GPR54 receptor antagonist with binding IC50 of 2.7 nM in competition with 125I-kisspeptin-10, blocks the stimulatory effects of kisspeptin on hypothalamus-pituitary-gonadal (HPG) axis. |
| PC-21150 |
ST2 inhibitor XY52
ST2 inhibitor
|
ST2 inhibitor XY52 is a specific small molecule inhibitor of soluble suppression of tumorigenesis-2 factor (ST2) with IC5 of 5.68 and 4.59 uM in ST2/IL-33 AlphaLISA and HEK-Blue reporter assays, repsectively. |
| PC-21149 |
25-Hydroxycholesterol
SREBP-1 inhibitor
|
25-Hydroxycholesterol (25-HC) is a specific sterol regulatory element-binding proteins (SREBP-1) inhibitor, decreases SREBP-1 protein level in cells. |
| PC-21144 |
4-ABAH
MPO inhibitor
|
4-ABAH is a specific irreversible inhibitor of myeloperoxidase (MPO) activity. |
| PC-21100 |
DSHN
NR0B2 agonist
|
DSHN is a small molecule activator of small heterodimer partner (SHP, NR0B2), functions as a transcriptional activator of SHP, inhibits HCC metastasis via SHP-mediated repression of Ccl2 signaling. |
| PC-21099 |
DSHN-OMe
NR0B2 agonist
|
DSHN-OMe (DSHN methyl ester) is a small molecule modulator of NR0B2, effectively reduces induction of LXR target gene ABCA1 by GW3965 (1 uM) in BMDMs with IC50 of 3.8 uM, reduces regulatory T cell expansion and impede breast cancer progression. |
| PC-21096 |
PSB-KD477
GPR18 agonist
|
PSB-KD477 is a potent, selective GPR18 agonist with EC50 of 454 nM, shows no activity against GPR55. |
| PC-21071 |
BDP-13176
Fascin-1 inhibitor
|
BDP-13176 is a small molecule inhibitor of actin-bundling protein Fascin-1 (Fscn1) with SPR and ITC Kd values of 85 and 50 nM, respectively, inhibits fascin-mediated actin bundling with IC50 of 240 nM. |
| PC-21057 |
C10M
CRP inhibitor
|
C10M is a small molecule inhibitor of C-reactive protein (CRP), inhibits the binding of pCRP to the physiological ligand phosphocholine (PC) with IC50 of 1.5 mM in ELISA assays. |
| PC-21028 |
PIP-199
RMI-MM2 inhibitor
|
PIP-199 is a small-molecule inhibitor of the Fanconi anemia complementation group M-RecQ-mediated genome instability protein (FANCM-RMI) protein-protein interaction, inhibits RMI core complex with Kd of 3.4 uM. |
