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Dilazep dihydrochloride

Chemical Structure : Dilazep dihydrochloride

CAS No.: 20153-98-4

Dilazep dihydrochloride

Catalog No.: PC-23923Not For Human Use, Lab Use Only.

Dilazep dihydrochloride is a small molecule adenosine reuptake inhibitor (AdoRI) and equilibrative nucleoside transporter 1 (ENT1) inhibitor (Ki=151.4 nM), shows cerebral and coronary vasodilating action through enhancement of effect of adenosine.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Dilazep dihydrochloride is a small molecule adenosine reuptake inhibitor (AdoRI) and equilibrative nucleoside transporter 1 (ENT1) inhibitor (Ki=151.4 nM), shows cerebral and coronary vasodilating action through enhancement of effect of adenosine.

Physicochemical Properties

M.Wt 677.61
Formula C31H46Cl2N2O10
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1,4-Diazepane-1,4-diyl)bis(propane-3,1-diyl) bis(3,4,5-trimethoxybenzoate) dihydrochloride

References

1. Wright NJ, et al. Nat Struct Mol Biol. 2019 Jul;26(7):599-606.

2. Zhang Y, et al. J Pharmacol Exp Ther. 1991 Sep;258(3):767-71.

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