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Cat. No. Product Name Information
PC-49091

RKN5755

β-arrestin1 ligand

RKN5755 is a small-molecule ligand of β-arrestin1, inhibits the enhanced migration of fibroblasts cocultured with cancer cells by binding to β-arrestin1 and interfering with β-arrestin1-mediated cofilin signaling pathways.
PC-49090

MCI-100

MCI-100 is a small molecule that displays greater potency than sulindac to protect RPE cells against oxidative damage, with lacked significant COX inhibitory activity, MCI-100 is more active than sulindac in protecting cells against oxidative damage.
PC-49085

ASR352

ASR352 is a small molecule NSC30049 analog, inhibits the growth of CRC bulk cells, sensitizs FOLFOX-resistant cells, and reduces the sphere formation capacity of CRC stem cells.
PC-49043

NP-C86

GAS5 inhibitor

NP-C86 is a small molecule that limits the degradation of GAS5 by blocking the interaction of long noncoding RNA (lncRNA) GAS5 and UPF1. NP-C86 binds to GAS5 with high affinity (Kd=153 nM) and stabilize GAS5 levels in vivo.
PC-49041

CD147 inhibitor AC-73

CD147 inhibitor

AC-73 is a potent, specific small molecule inhibitor of CD147 (Response Units=63, SPR assays), AC-73 disrupts CD147 dimerization and inhibits the motility and invasion of hepatocellular carcinoma cells.
PC-49031

PSB-CB-148

GPR18 antagonist

PSB-CB-148 is a potent, selective antagonist of GPR18.
PC-49030

PSB-KD107

GPR18 agonist

PSB-KD107 is a potent, selective GPR18 receptor agonist with EC50 of 0.562 uM and 1.78 uM for human and mouse GPR18, respectively.
PC-49029

PSB-CB-27

GPR18 antagonist

PSB-CB-27 is a potent, selective antagonist of GPR18 with IC50 of 650 nM, shows no inhibition on GPR55 and low affinity for CB1/CB2 receptors.
PC-49028

PSB-CB5

GPR18 antagonist

PSB-CB5 is a potent, selective antagonist of GPR18, inhibits GPR18 activation by tetrahydrocannabinol (THC) with IC50 of 279 nM in β-arrestin recruitment assays.
PC-49016

VSW1198

GGDPS inhibitor

VSW1198 is a potent, selective geranylgeranyl diphosphate synthase (GGDPS) inhibitor with IC50 of 45 nM, VSW1198 is highly specific for GGDPS over other enzymes in the isoprenoid biosynthesis (IBP) pathway.
PC-49007

KBP-066

Amylin/Calcitonin receptor agonist

KBP-066 is a potent, selective dual amylin and calcitonin receptor agonist induces an equally potent body weight loss across a broad dose range in obese rats.
PC-49001

MS21570

GPR171 antagonist

MS 21570 (MS0021570) is a small molecule antagonist of GPR171, antagonizes MS0015203 (Cat#PC-47110)-mediated increases in [35S]GTPγS binding in rat hypothalamic membranes (EC50 =0.6 nM).

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