| Cat. No. |
Product Name |
Information |
| PC-72496 |
TH8321
NUDT15 inhibitor
|
TH8321 (TH-8321) is a potent, selective NUDT15 inhibitor with IC50 of 35 nM. |
| PC-72492 |
SU056
YBX-1 inhibitor
|
SU056 (SU-056) is a specific small molecule that potently inhibits tumor growth and progression via Y box binding protein 1 (YBX-1) inhibition. |
| PC-72476 |
JTE-607
CPSF3 inhibitor
|
JTE-607 (JTE607) is a multiple cytokine inhibitor that potently suppresses production of proinflammatory cytokines, targets pre-messenger RNA endonuclease cleavage and polyadenylation specificity factor 3 (CPSF3). |
| PC-72464 |
PIP4K-IN-a131
PIP4K inhibitor
|
PIP4K-IN-a131 (PIP4K inhibitor a131) is a PIP4K lipid kinase inhibitor with IC50 of 1.9 uM (PI5P4Kα), selectively kills cancer cells, while protecting normal cells. |
| PC-72463 |
BAY-091
PIP4K2A inhibitor
|
BAY-091 (BAY091) is a potent and highly selective inhibitor of PIP4K2A with IC50 of 16 nM in the high ATP (2 mM) HTRF assay. |
| PC-72461 |
MLS000544460
EYA2 inhibitor
|
MLS000544460 (EYA2i) is a specific, allosteric inhibitor of Eya2 phosphatase with IC50 of 4.1 uM, KD of 2.0 uM, does not bind Eya3 ED, Eya1 and Eya4 ED. |
| PC-72451 |
NCGC00378430
SIX1-EYA2 inhibitor
|
NCGC00378430 (Compound 8430) is a novel small molecule compound that reduces the SIX1/EYA2 interaction in vitro with IC50 of 52 uM in the Alphascreen assay. |
| PC-72445 |
VLX600
Iron chelator
|
VLX600 (VLX-600) is a small molecule iron chelator and mitochondrial oxidative phosphorylation inhibitor, targets quiescent tumor cells and to inhibit mitochondrial respiration. |
| PC-72443 |
ONC212
GPR132 activator
|
ONC212 (ONC-212) is a potent anti-cancer small molecule, activator of an orphan GPCR GPR132 and Gαq signaling. |
| PC-72383 |
SRI-37330
TXNIP inhibitor
|
SRI-37330 (SRI 37330) is an orally available small molecule that regulates TXNIP expression, inhibits endogenous TXNIP mRNA expression (IC50=0.64 uM, INS-1 cells qRT-PCR assays). |
| PC-72381 |
HKB99
PGAM1 inhibitor
|
HKB99 (PGAM1 allosteric inhibitor HKB99) is a novel potent, cellularly active PGAM1 (Phosphoglycerate mutase 1) allosteric inhibitor, HKB99 is noncompetitive with the substrate 3-PG with IC50 of 0.85 uM in in vitro enzyme assays. |
| PC-72374 |
NF-56-EJ40
SUCNR1 (GPR91) antagonist
|
NF-56-EJ40 is a highly potent, human-selective antagonist of SUCNR1 (GPR91) with IC50 of 25 nM and Ki of 33 nM. |
