| Cat. No. |
Product Name |
Information |
| PC-22249 |
PRDX1 inhibitor 15
PRDX1 inhibitor
|
PRDX1 inhibitor 15 is a potent, selective and covalent peroxiredoxin (PRDX1) inhibitor with IC50 of 0.35 uM, covalently binds to Cys-173 of PRDX1 with KD of 0.37 uM, shows antiproliferative potency against colon cancer cells. |
| PC-22248 |
PRDX1 inhibitor H7
PRDX1 inhibitor
|
PRDX1 inhibitor H7 is a specific small molecule inhibitor of antioxidant enzyme peroxiredoxin I (Prdx I) with IC50 of 7.85 uM, induces leukemia-cell differentiation in vitro and in vivo. |
| PC-22243 |
FeM-1269
Ion mobilizer
|
FeM-1269 is a small molecule ion mobilizer, minimally aggregates and dose-dependently mobilizes iron across lipid bilayers, increases serum iron, transferrin saturation, hemoglobin and hematocrit in mouse model of anemia of inflammation. |
| PC-22240 |
FCW393
Sialyltransferase inhibitor
|
FCW393 is a potent, selective sialyltransferase inhibitor with IC50 of 7.8 uM and 9.48 uM for ST6GAL1 and ST3GAL3, does not inhibit ST3GAL1 and ST8SIA4 (IC50>100 uM), suppresses cancer metastasis. |
| PC-22222 |
Leflunomide
DHODH inhibitor
|
Leflunomide is a potent dihydroorotate dehydrogenase (DHODH) and pyrimidine synthesis inhibitor with IC50 of 208.5 nM in cell-free human DHODH enzyme inhibition assays. |
| PC-22221 |
HOSU-53 sodium
DHODH inhibitor
|
HOSU-53 sodium is selective and potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 0.95 nM in cell-free human DHODH enzyme inhibition assays. |
| PC-22220 |
HOSU-53
DHODH inhibitor
|
HOSU-53 is selective and potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 0.95 nM in cell-free human DHODH enzyme inhibition assays. |
| PC-22206 |
UNC-CA2-103
TLK2 inhibitor
|
UNC-CA2-103 is a potent, selective tousled like kinase 2 (TLK2) inhibitor with enzyme IC50 of 18 nM, exhibit excellent selectivity over TLK1 (16% inhibition at 0.5 μM). |
| PC-22201 |
NUDT5/NUDT14 inhibitor 9
NUDT5/NUDT14 inhibitor
|
NUDT5/NUDT14 inhibitor 9 is a potent dual cell-active NUDT5/NUDT14 inhibitor with SPR KD of 400 nM for purified human NUDT14 protein. |
| PC-22199 |
BAY R3401
Glycogen phosphorylase inhibitor
|
BAY R3401 is a potent, competive glycogen phosphorylase inhibitor, inhibits muscle glycogen phosphorylase a and b. |
| PC-22198 |
Bay W1807
Glycogen phosphorylase inhibitor
|
BAY W1807 is a potent, competive glycogen phosphorylase inhibitor with Ki of 1.6 nM for rabbit muscle glycogen phosphorylase b (GPb), inhibits muscle glycogen phosphorylase a and b. |
| PC-22184 |
Tacrolimus
FKBP ligand
|
Tacrolimus (FK506) is a macrocyclic lactone that binds to FK506 binding protein (FKBP) to form a complex, inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription, shows immunosuppressive properties. |
