| Cat. No. |
Product Name |
Information |
| PC-38247 |
GSK716
Zα1-antitrypsin inhibitor
|
GSK716 (GSK-716) is a potent inhibitor of Z α1-antitrypsin polymerisation, binds to Zα1-antitrypsin with a high-affinity (pKD=8.5). |
| PC-38246 |
BAM15
Mitochondrial uncoupler
|
BAM15 (Mitochondrial uncoupler BAM15) is a potent protonophore that uncouples the mitochondria without depolarizing the plasma membrane, oxidative phosphorylation (OXPHOS) uncoupler. |
| PC-38243 |
mitoNEET Ligand-1
mitoNEET ligand
|
mitoNEET Ligand-1 (NL-1) is a small molecule ligand of mitoNEET, a protein that regulate the oxidative capacity of the mitochondria. |
| PC-38227 |
DCLK1-IN-1
DCLK1 inhibitor
|
DCLK1-IN-1 is the first potent, selective inhibitor of the DCLK1 and DCLK2 kinases with IC50 of 9.5 nM and 31 nM in binding assays, respectively. |
| PC-38226 |
TH1760
NUDT15 inhibitor
|
TH1760 (TH 1760) is a first-in-class, potent, selective, cell-active NUDT15 inhibitor with IC50 of 25 nM. |
| PC-38225 |
TH7285
|
TH7285 is the negative control compound (IC50>100 uM) of TH1760, a potent, selective NUDT15 inhibitor. |
| PC-38224 |
Cas9 inhibitor 85
Cas9 inhibitor
|
Cas9 inhibitor 85 is a small-molecule ligand with anti-CRISPR/Cas9 activity with IC50 of 7 uM, binds to Apo-Cas9 and inhibits Cas9:gRNA complex formation. |
| PC-38216 |
UNC10245092
CIB1 inhibitor
|
UNC10245092 is a high affinity peptide inhibitor of Calcium and integrin binding protein 1 (CIB1), binds hydrophobic pocket on CIB1 with Kd of 29.4 nM.. |
| PC-38215 |
UNC10245350
CIB1 inhibitor
|
UNC10245351 is a N-terminal HIV Tat conjugate to UNC10245092, a CIB1 peptide inhibitor (Kd=192 nM), cell-penetrating. |
| PC-38214 |
H3B-120
CPS1 inhibitor
|
H3B-120 (H3B 120) is a selective allosteric inhibitor of Carbamoyl phosphate synthetase 1 (CPS1) with Ki of 1.4 uM, does not bind to CPS2. |
| PC-38213 |
H3B-616
CPS1 inhibitor
|
H3B-616 (H3B 616) is a potent, selective allosteric inhibitor of carbamoyl phosphate synthetase 1 (CPS1) with IC50 of 66 nM, demonstrates no appreciable inhibition of CPS2 (IC50>100 uM). |
| PC-38212 |
KLK6 inhibitor 32
KLK6 inhibitor
|
KLK6 inhibitor 32 is a potent and selective inhibitor of kallikrein‐related peptidase 6 (KLK6) with IC50 of 2.5 nM, high selectivity against KLK7, KLK8, Trypsin, Thrombin. |
