| Cat. No. |
Product Name |
Information |
| PC-38280 |
ENPP1 inhibitor 32
ENPP1 inhibitor
|
ENPP1 inhibitor 32 is a potent, cell-impermeable small molecule inhibitor of ENPP1 with Ki of < 2 nM. |
| PC-38276 |
KL201
Cryptochrome 1 modulator
|
KL201 (KL201) is an isoform-selective modulator of Cryptochrome 1 (CRY1), stabilize CRY1 but not CRY2. |
| PC-38275 |
UNC4850
CDYL1/2 inhibitor
|
UNC4850 (UNC-4850) is a specific small-molecule inhibitor toward CDY Chromodomain CDYL1/2 with Kd of 0.47/0.42 uM, >10-fold selectivity over CDY1, CBX5 and CBX7. |
| PC-38274 |
PI5P4K inhibitor 30
PI5P4K inhibitor
|
PI5P4K inhibitor 30 is a highly selective pan-PI5P4K covalent inhibitor with IC50 of 1.3/9.9 uM against PI5P4Kα/β, inhibits PI5P4Kγ by 22% at 1 uM.. |
| PC-38273 |
THZ-P1-2
PI5P4K inhibitor
|
THZ-P1-2 is a potent, selective, covalent pan-PI5P4K inhibitor with IC50 of 190/700 nM for PI5P4Kα/β, respectively. |
| PC-38272 |
NCT-504
PI5P4Kγ inhibitor
|
NCT-504 (NCT504) is a selective inhibitor of PI5P4Kγ with IC50 of 16 uM in 32P-ATP/PI5P incorporation assay, high selectivity against a panel of 442 kinases. |
| PC-38271 |
PI5P4K inhibitor 13
PI5P4K inhibitor
|
PI5P4K inhibitor 13 is a selective pan-PI5P4K covalent inhibitor with IC50 of 2.0/13 uM against PI5P4Kα/β, 100% inhibition of PI5P4Kγ at 1 uM (Kd=3.4 nM). |
| PC-38270 |
PI5P4Kγ inhibitor 40
PI5P4Kγ inhibitor
|
PI5P4Kγ inhibitor 40 is a selective, non-ATP-competitive, allosteric inhibitor of PI5P4Kγ with pIC50 of 6.2, does not inhibit PI5P4Kα/β with pIC50<4.6. |
| PC-38261 |
UNC4976
CBX7 modulator
|
UNC4976 (UNC-4976) is a potent cellular active positive allosteric modulator of CBX7, binds to CBX7 competitively with H3K27me3 peptides (IC50=20 nM), while increasing affinity for oligonucleotides. |
| PC-38260 |
UNC7040
CBX8 modulator
|
UNC7040 (UNC-7040) is a potent, specific positive allosteric modulator of CBX8 with EC50 of 0.84 uM in CBX8 reporter assays. |
| PC-38253 |
Aprotinin
Trypsin/Chymotrypsin inhibitor
|
Aprotinin is a single chain polypeptide isolated from bovine lung with antifibrinolytic and anti-inflammatory activities, inhibits trypsin and chymotrypsin with Ki of 0.06 pM and 9 nM respectively. |
| PC-38249 |
NR2F1 agonist C26
NR2F1 agonist
|
NR2F1 agonist C26 is a specific agonist of nuclear receptor NR2F1, significantly induces luciferase expression by 1.7- and 1.9-fold at 0.5 and 1 uM in RARE-luciferase bioassays. |
