| Cat. No. |
Product Name |
Information |
| PC-25174 |
BMS-262084
Tryptase inhibitor, FXIa inhibitor
|
BMS-262084 is a potent and highly selective inhibitor of human tryptase with IC50 of 4 nM, >100-fold selective over Plasmin, Thrombin, uPA and tPA, also is an irreversible inhibitor of factor Xia with IC50 of 2.8 nM, shows antithrombotic effects. |
| PC-25173 |
Pyrabactin
ABA receptor agonist
|
Pyrabactin is a specific, synthetic abscisic acid (ABA) agonist that selectively inhibits seed germination, promotes interactions between HAB1 and PYR1, PYL1 or PYL3. |
| PC-25172 |
AMF4
ABA receptor agonist
|
AMF4 is synthetic ABA-mimicking ligand and potent agonist of PYL proteins PYR1, PYL1, PYL2, and PYL7 with binding EC50 of 47-120 nM, induces genes involved in abiotic-stress resistance, regulates ABA-responsive genes in Arabidopsis plants. |
| PC-25171 |
Cyanabactin
ABA receptor agonist
|
Cyanabactin is a potent and selective plant hormone abscisic acid (ABA) receptor agonist that preferentially activates Pyrabactin Resistance 1 (PYR1) with low nanomolar potency, exhihibits a wide spectrum of ABA-like activities. |
| PC-25170 |
ABA receptor agonist iCB
ABA receptor agonist
|
ABA receptor agonist iCB is a novel synthetic abscisic acid (ABA) receptor agonist with broad-spectrum activation across the three receptor subtypes, has IC50 of 0.16 uM in seedling establishment inhibition assay. |
| PC-25150 |
MIF inhibitor 4-IPP
MIF inhibitor
|
MIF inhibitor 4-IPP is a specific, irreversible, suicide substrate inhibitor of macrophage migration inhibitory factor (MIF). |
| PC-25149 |
LIBX-A403
ACSL4 inhibitor
|
LIBX-A403 is a potent, selective Acyl-coenzyme A synthetase long-chain family member 4 (ACSL4) inhibitor with IC50 of 49 nM and MST KD of 0.29 uM, with no activity against ACSL3. |
| PC-25143 |
MMTC/57E
SNAT2 inhibitor
|
MMTC/57E (Compound 57E) is a selective small molecule inhibitor of sodium-coupled neutral amino acid transporter 2 (SNAT2, SLC38A2) with IC50 of 0.8 uM. |
| PC-25137 |
GI-Y1
GSDMD inhibitor
|
GSDMD inhibitor Y1 (GI-Y1) is a selective gasdermin D (GSDMD) inhibitor, binds to GSDMD with SPR KD of 7.69 uM, shows cardioprotective effects. |
| PC-25120 |
UNC7437
IPMK inhibitor
|
UNC7437 is a potent selective inhibitor of inositol phosphate multikinase (IPMK) with IC50 of 26.2 nM, decreased cellular proliferation and tritiated inositol phosphate levels in human U251-MG glioblastoma cells. |
| PC-25115 |
M6766
ERO1α inhibitor
|
M6766 is a potent, selective inhibitor of endoplasmic reticulum oxidoreductase 1α (ERO1α) with IC50 of 1.4 uM and KD of 1.1 uM. |
| PC-25093 |
Simepdekinra
IL-17A modulator
|
Simepdekinra is a potent, selective modulator of interleukin 17A (IL-17A). |
