| Cat. No. |
Product Name |
Information |
| PC-23762 |
SH514
IRF4 inhibitor
|
SH514 is a specific small molecule inhibitor of interferon regulatory factor 4 (IRF4) with IC50 of 2.63 uM, inhibits proliferation of IRF4-high-expressing NCI-H929 and MM.1R MM cells with IC50 of 0.08 uM and 0.11 uM, respectively. |
| PC-23758 |
MTDH-SND1 PPI inhibitor C19
MTDH-SND1 inhibitor
|
MTDH-SND1 PPI inhibitor C19 is a small-molecule inhibitor of MTDH-SND1 PPI with IC50 of 487 nM, directly binds to the SND1-purified protein, degrades SND1 and downregulates downstream at the protein level. |
| PC-23750 |
Dauricine
STK11 agonist
|
Dauricine, a bisbenzylisoquinoline alkaloid in Menispermum dauricum, has anti-inflammatory activity, Dauricine is a natural agonist of STK11 (Serine/threonine kinase 11). |
| PC-23749 |
Benurestat
Urease inhibitor
|
Benurestat is a reversible competitive inhibitor of gut bacterial urease, inhibits ammonia production by urease-encoding gut bacteria, inhibits urease activity in mouse fecal suspensions ex vivo with IC50 of 2.5 uM. |
| PC-23738 |
MTB-9655
ACSS2 inhibitor
|
MTB-9655 is a potent, selective and orally bioavailable Acetyl-Coenzyme A Synthetase 2 (ACSS2) inhibitor with biochemical IC50 of 0.15 nM and EC50 of 3 nM in cellular assays. |
| PC-23732 |
Ln268
PGK1 inhibitor
|
Ln268 is a potent Lin28 inhibitor, inhibits Lin28:pre-let-7d complex formation in a dose-dependent manner, inhibits Lin28b at both mRNA and protein level, specifically inhibits various Lin28-positive cancer cells. |
| PC-23731 |
Z57346765
PGK1 inhibitor
|
Z57346765 is a phosphoglycerate kinase 1 (PGK1) inhibitor, significantly reduces the metabolic enzyme activity of PGK1 in glycolysis, inhibits KIRC cell proliferation. |
| PC-23722 |
QP5020
QPCTL inhibitor
|
QP5020 is a potent inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with IC50 of 15 nM. |
| PC-23698 |
SEPT9 inhibitor 8b
SEPT9 inhibitor
|
SEPT9 inhibitor 8b is a small molecule inhibitor of Septin 9 (SEPT9) with IC50 of 95 uM in fluorescence polarization (FP) assays, and binding KD of 22 uM, disrupts the structure of SEPT9, microtubules, and actin filaments. |
| PC-23697 |
Neocarzilin A
VAT1 inhibitor
|
Neocarzilin A (NCA) is a potent inhibitor of cancer cell migration, irreversibly binds to and inhibits the synaptic vesicle membrane protein VAT-1. |
| PC-23673 |
TD-198946
Runx1 modulator
|
TD-198946 is a small molecule disease-modifying osteoarthritis compound, effectively repairs cartilage by promoting chondrogenic differentiation and halt osteoarthritis (OA) progression, exerts its effect through the regulation of Runx1 expression. |
| PC-23649 |
Genipin
UCP2 inhibitor
|
Genipin is a specific small molecule inhibitor of uncoupling protein 2 (UCP2), inhibits UCP2-mediated mitochondrial proton leak. |
