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RNase L-IN-2

Chemical Structure : RNase L-IN-2

CAS No.: 357618-26-9

RNase L-IN-2

Catalog No.: PC-70265Not For Human Use, Lab Use Only.

RNase L-IN-2 is a small-molecule activator of RNase L with EC50 of 22 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

RNase L-IN-2 is a small-molecule activator of RNase L with EC50 of 22 uM; shows broad-spectrum antiviral activity against diverse types of RNA viruses, including the human pathogen human parainfluenza virus type 3, with no cytotoxic at the effective concentrations.

Physicochemical Properties

M.Wt 298.36
Formula C16H14N2O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(3-hydroxyphenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one

References

1. Thakur CS, et al. Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9585-90.

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