| Cat. No. |
Product Name |
Information |
| PC-72762 |
CVN424
GPR6 antagonist
|
CVN424 (CVN 424) is a highly potent, selective, brain-penetrant, orally active GPR6 inverse agonist with EC50 of 38 nM. |
| PC-72748 |
PDDC
nSMase2 inhibitor
|
PDDC is the first potent, selective, orally-available, and brain-penetrable nSMase2 (neutral sphingomyelinase 2) inhibitor with pIC50 of 6.57. |
| PC-72746 |
Sari 59-801
|
SaRI 59-801 is an orally effective hypoglycemic compound, decreases blood glucose in several species and to elevate plasma insulin in rats and mice. |
| PC-72745 |
CHD1Li 6.11
CHD1L inhibitor
|
CHD1Li 6.11 is a first in class, orally bioavailable oncogenic CHD1L inhibitor with 3.3 uM (CHD1L-cat enzyme activity). |
| PC-72727 |
T417
PBX1 inhibitor
|
T417 (PBX1 inhibitor T417, TCRS-417) is a novel small molecule compound capable of docking to the interface between PBX1 and its cognate DNA target sequence, potently interferes with the PBX1-DNA interaction with IC50 of 6.58 uM. |
| PC-72720 |
FGF23 inhibitor 13a
FGF23 inhibitor
|
FGF23 inhibitor 13a (FGF23-IN-13a) is a ZINC13407541 analogue with enhanced drug-like properties, inhibits FGF23 with IC50 of 0.14 uM. |
| PC-72719 |
ZINC13407541
FGF23 inhibitor
|
ZINC13407541 is a small molecule antagonist for FGF23, inhibits FGF-23 signaling with IC50 of 0.45 uM. |
| PC-72714 |
AAA-10
BSH inhibitor
|
AAA-10 (AAA10) is a second-generation gut-restricted pan-bile salt hydrolase (BSH) enzyme inhibitor. |
| PC-72713 |
GAS41 YEATS inhibitor 19
GAS41 YEATS domain inhibitor
|
GAS41 YEATS inhibitor 19 (GAS41 YEATS-IN-19) is potent, selective, cell-permeable dimeric inhibitor of GAS41 YEATS domain with IC50 of 18 nM (AlphaScreen competition assay). |
| PC-72703 |
CASK inhibitor 18
CASK inhibitor
|
CASK chemical probe 18 is a highly potent and selective CASK inhibitor with IC50 of 22 nM. |
| PC-72687 |
Ethanimidothioic acid
Scramblase inhibitor
|
Ethanimidothioic acid (R5421) is an inhibitor of platelet scramblase activity. |
| PC-72667 |
UNC10245131
CIB1 inhibitor
|
UNC10245131 (UNC 10245131) is a potent, selective cyclic peptide inhibitor of calcium and integrin binding protein 1 (CIB1) with ITC Kd of 6.17 nM. |
