| Cat. No. |
Product Name |
Information |
| PC-62874 |
ARN726
NAAA inhibitor
|
ARN726 is a potent, selective, orally bioavailable N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 of 63 nM (r-NAAA) and 27 nM (h-NAAA). |
| PC-62873 |
ARN077
NAAA inhibitor
|
ARN077 is the first potent, selective N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 of 7 nM on both rat NAAA and human NAAA. |
| PC-62859 |
SB1301
Lin28 inhibitor
|
SB1301 (Lin28-IN-1) is a small-molecule inhibitor disrupting the protein-RNA interaction of LIN28 and Let-7 with FRET IC50 of 4 uM. |
| PC-62825 |
CCG-203971
|
CCG-203971(CCG203971) is a potent Rho/MKL1/SRF transcriptional pathway inhibitor, suppresses PC-3 cell migration in scratch wound assays (IC50=4.2 uM), blocks nuclear localization and activity of MRTF-A in SK-Mel-147 cells. |
| PC-62753 |
Sepin-1
|
Sepin-1 is a small molecule, noncompetitive separase inhibitor with IC50 of 14.8 uM. |
| PC-62745 |
DB2115
PU.1 inhibitor
|
DB2115 is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 1.0 nM. |
| PC-62744 |
DB2313
PU.1 inhibitor
|
DB2313 is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 29 nM. |
| PC-62693 |
SLC25A20-IN-21
|
SLC25A20-IN-21 is a SLC25A20 ligand that increases long-chain (>C14) acylcarnitine content and reduces maximal exogenous fatty acid oxidation in HSC-5 cells. |
| PC-62689 |
Brequinar
DHODH inhibitor
|
Brequinar (DuP785, NSC 368390) is a potent and selective inhibitor of DHODH with IC50 of 20 nM, triggers differentiation in the ER-HoxA9, U937, and THP1 cells with an ED50 of 1 uM. |
| PC-62688 |
Perhexiline maleate
|
Perhexiline maleate (WSM 3978G) is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2). |
| PC-62687 |
Perhexiline
|
Perhexiline is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2). |
| PC-62671 |
MJN228
NUCB1 ligand
|
MJN228 is a selective ligand for the lipid-binding protein nucleobindin 1 (NUCB1) with IC50 of 3.3 uM (blocks AEA-DA probe labeling of NUCB1). |
