| Cat. No. |
Product Name |
Information |
| PC-72871 |
NERx 329
RPA inhibitor
|
NERx 329 (RPAi 329, NERx329) is a novel potent, specific inhibitor of replication protein A (RPA), demonstrated potent RPA inhibitory activity in vitro, in vivo, and in cellular assays. |
| PC-72865 |
MN132.0262
APOBEC3G inhibitor
|
MN132.0262 is a small molecule, dual inhibitor of A3G (APOBEC3G, IC50=20 uM). |
| PC-72864 |
MN256.0102
APOBEC3G inhibitor
|
MN256.0102 is a small-molecule APOBEC3G DNA cytosine deaminase inhibitor with IC50 of 3.9 uM. |
| PC-72863 |
MN256.0105
APOBEC3G inhibitor
|
MN256.0105 is a small-molecule APOBEC3G DNA cytosine deaminase inhibitor with IC50 of 4.3 uM. |
| PC-72855 |
Pixatimod
Heparanase inhibitor
|
Pixatimod (PG545) is a heparan sulfate (HS) mimetic and anticancer agent and a potent inhibitor of heparanase. |
| PC-72846 |
Simufilam hydrochloride
Filamin A corrector
|
Simufilam hydrocloride (PTI-125) is a small molecule targeting scaffolding protein filamin A (FLNA), preferentially binds altered FLNA and restores its native conformation. |
| PC-72845 |
PTI-125
Filamin A corrector
|
PTI-125 (Simufilam, Sumifilam) is a small molecule targeting scaffolding protein filamin A (FLNA), preferentially binds altered FLNA and restores its native conformation. |
| PC-72843 |
RAGE229
RAGE inhibitor
|
RAGE229 (RAGE-229) is a specific antagonist of ctRAGE-DIAPH1 interaction, high potently binds to cytoplasmic tail of RAGE (ctRAGE) with KD of 2 nM. |
| PC-72839 |
BOS-318
Furin inhibitor
|
BOS-318 (BOS318) is a potent, highly selective, cell-permeable furin inhibitor with IC50 of 1.9 nM, Ki of 0.4 nM. |
| PC-72838 |
KM04794
UPR inhibitor
|
KM04794 (KM-04794) is a chemical chaperone-like small molecule modulator of endoplasmic reticulum (ER) proteostasis and alleviates ER stress, inhibits UPR signaling with IC50 of 10 uM. |
| PC-72833 |
ChemR23 inhibitor 14f
ChemR23 inhibitor
|
ChemR23 inhibitor 14f is a potent and orally active inhibitor of ChemR23 (IC80=12 nM), a G protein-coupled receptor (GPCR) expressed on the surface of plasmacytoid dendritic cells (pDCs). |
| PC-72831 |
Nek1 inhibitor 10f
Nek1 inhibitor
|
Nek1 inhibitor 10f is a potent, selective NIMA-related kinase 1 (Nek1) inhibitor with IC50 of 330 nM. |
