| Cat. No. |
Product Name |
Information |
| PC-62874 |
ARN726
NAAA inhibitor
|
ARN726 is a potent, selective, orally bioavailable N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 of 63 nM (r-NAAA) and 27 nM (h-NAAA). |
| PC-62873 |
ARN077
NAAA inhibitor
|
ARN077 is the first potent, selective N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 of 7 nM on both rat NAAA and human NAAA. |
| PC-62861 |
PNPLA4-IN-1
PNPLA4 inhibitor
|
PNPLA4-IN-1 is a potent, selective, and irreversible PNPLA4 (patatin-like phospholipase domain-containing protein 4) inhibitor with IC50 of 1.8 uM (separated membrane proteome fraction), shows in-cell inhibition of PNPLA4 with IC50 of 11.7 uM. |
| PC-62860 |
PF-6808472
|
PF-6808472 (XO44) is a sulfonyl fluoride chemical probe that covalently labels a broad swath of the intracellular kinome with high efficiency. |
| PC-62859 |
SB1301
Lin28 inhibitor
|
SB1301 (LIN28-Let-7 inhibitor) is a small-molecule inhibitor disrupting the protein-RNA interaction of LIN28 and Let-7 with FRET IC50 of 4 uM. |
| PC-62825 |
CCG-203971
Rho/MKL1/SRF inhibitor
|
CCG-203971(CCG203971) is a potent Rho/MKL1/SRF transcriptional pathway inhibitor, suppresses PC-3 cell migration in scratch wound assays (IC50=4.2 uM), blocks nuclear localization and activity of MRTF-A in SK-Mel-147 cells. |
| PC-62824 |
CCG-232601
MRTF/SRF inhibitor
|
CCG-232601 is a potent (IC50=0.55 uM), orally bioavailable inhibitor of Rho/MRTF/SRF transcriptional pathway that target transcriptional factor MRTF. |
| PC-62786 |
VU6001221
Choline transporter inhibitor
|
VU6001221 is a potent choline transporter (CHT) inhibitor with IC50 of 270 nM. |
| PC-62785 |
ML352
Choline transporter inhibitor
|
ML352 (VU0476201) is a potent, selective choline transporter (CHT) inhibitor with Ki of 92 nM. |
| PC-62753 |
Sepin-1
|
Sepin-1 is a small molecule, noncompetitive separase inhibitor with IC50 of 14.8 uM. |
| PC-62745 |
DB2115
PU.1 inhibitor
|
DB2115 is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 1.0 nM. |
| PC-62744 |
DB2313
PU.1 inhibitor
|
DB2313 is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 29 nM. |
