| Cat. No. |
Product Name |
Information |
| PC-20302 |
HTS13286
AQP9 inhibitor
|
HTS13286 is a selective AQP9 inhibitor with IC50 of 1.5 uM (inhibition of CHO-AQP9 cell water permeability). |
| PC-20301 |
RF03176
AQP9 inhibitor
|
RF03176 is a selective AQP9 inhibitor with IC50 of 1.3 uM (inhibition of CHO-AQP9 cell water permeability). |
| PC-20300 |
TGN-020
AQP4 inhibitor
|
TGN-020 (TGN020) is a potent, selective aquaporin 4 (AQP4) inhibitor with IC50 of 3 uM. |
| PC-20274 |
SPT inhibitor compound-2
SPT inhibitor
|
SPT inhibitor compound-2 is a potent, orally active serine palmitoyltransferase (SPT) inhibitor with IXC50 of 0.51 nM in cell-free assays. |
| PC-20224 |
Compound 30666
IgH gene enhancer inhibitor
|
Compound 30666 is a specific small molecule inhibitor of IgH enhancer transcriptional activity with IC50 of 2.1 uM, inhibits immunoglobulin production by MM cells. |
| PC-20213 |
2,5-pyridinedicarboxylic acid
MIF2 inhibitor
|
2,5-pyridinedicarboxylic acid is a highly selective D-dopachrome tautomerase (D-DT, MIF2) inhibitor with Ki of 17.2 uM, 79-fold selectivity over MIF, effectively blocks the D-DT-induced activation of CD74. |
| PC-20166 |
TMX-4084
PIP4K2C binder
|
TMX-4084 (TMX4084) is a highly potent, selective PIP4K2C binder with KD of 7.3 nM, shows no affinity for PIP4K2B and PIP4K2A (KD>10 uM). |
| PC-20165 |
TMX-4102
PIP4K2C binder
|
TMX-4102 (TMX4102) is a highly potent, selective PIP4K2C binder with KD of 0.45 nM, shows no affinity for PIP4K2B and PIP4K2A (KD>10 uM). |
| PC-20158 |
CKi-4
Covalent creatine kinase inhibitor
|
Creatine kinase inhibitor CKi-4 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.3 uM, depletes creatine phosphagen energetics in cells. |
| PC-20157 |
CKi-6
Covalent creatine kinase inhibitor
|
CKi-6 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.6 uM, depletes creatine phosphagen energetics in cells. |
| PC-20155 |
MitoCKi
Covalent creatine kinase inhibitor
|
MitoCKi (Creatine kinase inhibitor CKi-26) is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 185 nM, depletes creatine phosphagen energetics in cells. |
| PC-20154 |
Creatine kinase inhibitor CKi-1
Covalent creatine kinase inhibitor
|
Creatine kinase inhibitor CKi-1 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 1.2 uM, depletes creatine phosphagen energetics in cells. |
