| Cat. No. |
Product Name |
Information |
| PC-25176 |
BMS-354326
Tryptase inhibitor
|
BMS-354326 is a highly potent, selective tryptase inhibitor with IC50 of 1.8 nM, shows excellent selectivity against trypsin and most other related serine proteases. |
| PC-25175 |
BMS-363131
Tryptase inhibitor
|
BMS-363131 is a potent, selective inhibitor of tryptase with IC50 of <1.7 nM, having excellent selectivity versus other serine proteases including trypsin. |
| PC-25174 |
BMS-262084
Tryptase inhibitor, FXIa inhibitor
|
BMS-262084 is a potent and highly selective inhibitor of human tryptase with IC50 of 4 nM, >100-fold selective over Plasmin, Thrombin, uPA and tPA, also is an irreversible inhibitor of factor Xia with IC50 of 2.8 nM, shows antithrombotic effects. |
| PC-25172 |
AMF4
ABA receptor agonist
|
AMF4 is synthetic ABA-mimicking ligand and potent agonist of PYL proteins PYR1, PYL1, PYL2, and PYL7 with binding EC50 of 47-120 nM, induces genes involved in abiotic-stress resistance, regulates ABA-responsive genes in Arabidopsis plants. |
| PC-25150 |
MIF inhibitor 4-IPP
MIF inhibitor
|
MIF inhibitor 4-IPP is a specific, irreversible, suicide substrate inhibitor of macrophage migration inhibitory factor (MIF). |
| PC-25149 |
LIBX-A403
ACSL4 inhibitor
|
LIBX-A403 is a potent, selective Acyl-coenzyme A synthetase long-chain family member 4 (ACSL4) inhibitor with IC50 of 49 nM and MST KD of 0.29 uM, with no activity against ACSL3. |
| PC-25143 |
MMTC/57E
SNAT2 inhibitor
|
MMTC/57E (Compound 57E) is a selective small molecule inhibitor of sodium-coupled neutral amino acid transporter 2 (SNAT2, SLC38A2) with IC50 of 0.8 uM. |
| PC-25120 |
UNC7437
IPMK inhibitor
|
UNC7437 is a potent selective inhibitor of inositol phosphate multikinase (IPMK) with IC50 of 26.2 nM, decreased cellular proliferation and tritiated inositol phosphate levels in human U251-MG glioblastoma cells. |
| PC-25050 |
NNZ-2591
Neuroprotective agent
|
Ercanetide (NNZ-2591, NNZ 2591) is an analogue of endogenous diketopiperazine cyclo-glycyl-proline (cyclic GP), shows neuroprotective effect. |
| PC-25025 |
Rivasterat
Endothelial dysfunction blocker
|
Rivasterat (CU06-1004, Sac-1004) is a small molecule vascular leakage blocker and endothelial dysfunction blocker, inhibits endothelial hyperpermeability induced by VEGF, histamine and thrombin via stabilization of cortical actin ring and AJ proteins at the cell-cell junction. |
| PC-25014 |
MG-257
Galectin-3/TREM2 inhibitor
|
MG-257 is a small molecule ligand of galectin-3, impedes interaction between TREM2 and galectin-3 with IC50 of 91 nM in TR-FRET assays, attenuates TREM2 signaling. |
| PC-25008 |
Veonetinib
Tyrosine kinase inhibitor
|
Veonetinib (Example 3) is an effective inhibitor of tyrosine kinase, exhibits IC50 values of 0.1 μM and 0.4 μM in A549 cells and LOVO cells, respectively. |
