hClpP inhibitor TG42

Chemical Structure : hClpP inhibitor TG42

Catalog No.: PC-25349Not For Human Use, Lab Use Only.

hClpP inhibitor TG42 is a potent and selective inhibitor of hClpP with IC50 of 0.39 uM, efficiently blocks proteolysis.

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Biological Activity

hClpP inhibitor TG42 is a potent and selective inhibitor of hClpP with IC50 of 0.39 uM, efficiently blocks proteolysis.
TG42 reduces cell viability in Huh7 cells, induces apoptotic cell death in Huh7 cells.

Physicochemical Properties

M.Wt	394.39
Formula	C24H14N2O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(1,3,4-oxadiazol-2-yl)phenyl 2-(2-ethynylnaphtho[2,1-b]furan-1-yl)acetate

References

1. Thomas F Gronauer, et al. Chem Commun (Camb). 2018 Aug 28;54(70):9833-9836.

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