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5-O-Methylvisammioside

Chemical Structure : 5-O-Methylvisammioside

CAS No.: 84272-85-5

5-O-Methylvisammioside (5OMV)

Catalog No.: PC-25387Not For Human Use, Lab Use Only.

5-O-Methylvisammioside (5OMV) is a flavonol compound derived from the traditional Chinese medicine plant Saposhnikovia divaricat, inhibits vasospasm induced by High Mobility Group Box 1 (HMGB1) protein, also inhibits intestinal concentrative nucleoside transporter 2 (CNT2) with IC50 of 11.22 uM, inhibits intestinal purine nucleoside absorption.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

5-O-Methylvisammioside (5OMV) is a flavonol compound derived from the traditional Chinese medicine plant Saposhnikovia divaricat, inhibits vasospasm induced by High Mobility Group Box 1 (HMGB1) protein, also inhibits intestinal concentrative nucleoside transporter 2 (CNT2) with IC50 of 11.22 uM, inhibits intestinal purine nucleoside absorption.

Physicochemical Properties

M.Wt 452.46
Formula C22H28O10
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-4-Methoxy-7-methyl-2-(2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)-2,3-dihydro-5H-furo[3,2-g]chromen-5-one

References

1. Hou W, et al. PLoS One. 2025 May 5;20(5):e0322056.

2. Mai S, et al. Biochem Pharmacol. 2025 Aug 13:117236.

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