| Cat. No. |
Product Name |
Information |
| PC-27560 |
EZ-482
ApoE ligand, ApoE inhibitor
|
EZ-482 is a small molecule ligand of Apolipoprotein E (ApoE), binds to the C-terminal domains of both ApoE3 and ApoE4 with KD of approximately 8 μM, blocks heparin binding to the N-terminal domain. |
| PC-27550 |
Rhoifolin
CAS 17306-46-6
|
Rhoifolin is a natural flavonoid with anti-inflammatory and antiparasitic potential, is a a direct potassium channel modulatory factor 1 (KCMF1) binder that stabilizes AMPKα and ameliorates MASLD, also inhibits the specific binding site of ALDH2-PKCδ, significantly increases chemosensitivity. |
| PC-27549 |
Helveticoside
CAS 630-64-8
|
Helveticoside is a natural compound extract of Descurainia sophia, induces reciprocal gene regulation in A549 human lung cancer cells, shows p53-dependent anti-cancer activity of aginst colorectal cancer cells SW480 and HCT116. |
| PC-27535 |
HA-CD44 inhibitor JE22
CD44 inhibitor
|
HA-CD44 inhibitor JE22 is a small molecule Hyaluronic acid (HA)-CD44 interaction inhibitor, effectively blocks HA-CD44 binding, shows antiproliferative activity with EC50 of 8 uM against the CD44+ breast cancer tumor line MDA-MB-231. |
| PC-27534 |
HA-CD44 inhibitor 4
CD44 inhibitor
|
HA-CD44 inhibitor 4 is a potential Hyaluronic acid (HA)-CD44 interaction inhibitor, effectively blocks HA-CD44 binding, shows antiproliferative activity against MDA-MB-231 cells with EC50 of 3.58 uM. |
| PC-27533 |
HA-CD44 inhibitor 3
CD44 inhibitor
|
HA-CD44 inhibitor 3 is a potential Hyaluronic acid (HA)-CD44 interaction inhibitor, effectively blocks HA-CD44 binding, shows antiproliferative activity against MDA-MB-231 cells with EC50 of 4.24 uM. |
| PC-27532 |
HA-CD44 inhibitor 2
CD44 inhibitor
|
HA-CD44 inhibitor 2 is a potential Hyaluronic acid (HA)-CD44 interaction inhibitor, effectively blocks HA-CD44 binding, shows antiproliferative activity against MDA-MB-231 cells with EC50 of 0.59 uM. |
| PC-27531 |
HA-CD44 inhibitor 1
CD44 inhibitor
|
HA-CD44 inhibitor 1 is a potential Hyaluronic acid (HA)-CD44 interaction inhibitor, effectively blocks HA-CD44 binding, shows antiproliferative activity against MDA-MB-231 cells with EC50 of 1.77 uM. |
| PC-27529 |
Polyphyllin VI
CAS 55916-51-3
|
Polyphyllin VI (PP-VI, PPVI) is a steroidal saponin isolated from Paris polyphylla with broad and strong anticancer effect and anti-metastatic activity, increases expression of Rell2 (Receptor expressed in lymphoid tissue (RELT)-like 2) and decreases level of miR-18a in 4T1 and MDA-MB-231 cells. |
| PC-27527 |
Rbin-2
Midasin inhibitor
|
Rbin-2 is a potent, reversible and selective inhibitor of AAA+ protein Midasin (Mdn1), inhibits eukaryotic ribosome biogenesis. |
| PC-27524 |
SAIT-PDZ-5179
GIPC1 inhibitor
|
SAIT-PDZ-5179 is a small molecule inhibitor of GAIP-interacting protein C terminus 1 (GIPC1), selectively target the PDZ domain of GIPC1 with ITC KD of 943 nM. |
| PC-27518 |
Zumododstat
DHODH inhibitor
|
Zumododstat is a potent, selective inhibitor of dihydro-orotate dehydrogenase (DHODH). |
