| Cat. No. |
Product Name |
Information |
| PC-45088 |
SP-420
Iron chelating agent
|
Petadeferitrin (SP-420) is a desferrithiocin analogue and iron chelating agent that has iron-clearing efficiency with ICE value of 26.7, SP-420 is more potent than desferrithiocin. |
| PC-45513 |
HQ-415
Metal chelator, TDP-43 modulator
|
HQ-415 is a derivative of 8-hydroxyquinoline that has selectivity for rescuing the distinct toxicities caused by the expression of TDP-43 with EC50 of 15 uM, α-synuclein or polyglutamine proteins. |
| PC-42072 |
BAPTA
Mg2+ chelator
|
BAPTA is a cell-permeant, calcium-specific chelator with high selectivity over Mg2+. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-28054 |
MOG (35-55) mouse, rat
MOG peptide
|
MOG (35-55) mouse, rat is a myelin oligodendrocyte glycoprotein (MOG) peptide derived from the extracellular domain of MOG protein and key immunodominant epitope extensively utilized in the study of autoimmune demyelinating diseases of the central nervous system (CNS), induce experimental autoimmune encephalomyelitis (EAE) in susceptible animal models, particularly C57BL/6 mice. |
| PC-28053 |
MOG(35-55) amide Mouse, Rat
MOG peptide
|
MOG(35-55) peptide (mouse/rat sequence) is a myelin oligodendrocyte glycoprotein (MOG) peptide derived from the extracellular domain of MOG protein and key immunodominant epitope extensively utilized in the study of autoimmune demyelinating diseases of the central nervous system (CNS), induce experimental autoimmune encephalomyelitis (EAE) in susceptible animal models, particularly C57BL/6 mice. |
| PC-27993 |
α-glucosidase inhibitor 9f
alpha-glucosidase inhibitor
|
α-glucosidase inhibitor 9f is a potent, competitive inhibitor of alpha-glucosidase (α-glucosidase) with IC50 of 100 nM. |
| PC-27927 |
Spinosyn D
CAS 131929-63-0
|
Spinosyn D is the active ingredient of spinosad, which is a natural pesticide against a wide variety of insect pest species. |
| PC-27926 |
Spinosad
EGFR inhibitor
|
Spinosad is a pediculicide mixture of spinosyn A and spinosyn D (in an approximately 5:1 ratio, respectively), shows selective activity against a wide variety of insect pest species, effectively suppresses cell proliferation of lung adenocarcinoma (LUAD), disrupts the interaction between CHRNA5 and EGFR. |
| PC-27925 |
Spinosyn A
ASS1 activator
|
Spinosyn A is a polyketide insecticide in Saccharopolyspora spinosa, suppresses breast tumor cell proliferation and growth by binding to and activating Argininosuccinate synthase (ASS1), has potential inhibitory effects on a variety of cancer cells. |
