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Cat. No. Product Name Information
PC-49807

Muramyl Dipeptide

Muramyl Dipeptide is a naturally occurring component of bacterial cell walls that has the capacity to activate macrophages, is an immunological adjuvant.
PC-49766

CNS-11

Alpha-synuclein inhibitor

CNS-11 is a small molecules capable of disassembling preformed alpha-synuclein fibrils, may exert it's disaggregating effects on the N terminus of the fibril core.
PC-49756

NB-598 maleate

Squalene epoxidase inhibitor

NB-598 (NB598) is a potent competitive inhibitor of squalene epoxidase (SQLE, SE, squalene monooxygenase) with IC50 of 4.4 nM (rat SE), inhibits microsomal squalene epoxidase from dog liver and Hep G2 cells with IC50 of 2.0 and 0.75 nM, respectively.
PC-49755

MM0299 analog 13

Lanosterol synthase inhibitor

MM0299 analog 13 (MM 0299 derivative 13) is a potent, selective, orally bioavailable, brain-penetrant inhibitor of lanosterol synthase (LSS, competition EC50=28.7 nM) with anti-proliferative activity.
PC-49751

Cl-NIO

DDAH-1 inhibitor

Cl-NIO is a potent, selective inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) with Ki of 1.3 uM, > 500-fold selectivity against arginase and endothelial nitric oxide synthase.
PC-49741

Compound 7930079

Troponin C modulator

Compound 7930079 is a small molecule that increase calcium sensitivity without altering systolic calcium concentration and strengthening cardiac function, is a high affinity binder of Troponin C N-terminal domain (cNTnC) with Kd of 1.45 uM.
PC-49740

BI-6c9

Bid inhibitor

BI-6C9 is a specific small molecule inhibitor of BH3 interacting-domain death agonist (Bid) with Kd of 20 uM, blocks the release of both cytochrome c and second mitochondria-derived activator of caspase from mitochondria.
PC-49726

Seletracetam

SV2A ligand

Seletracetam (ucb 44212) is a high affinity for the synaptic vesicle protein 2A (SV2A) than levetiracetam with 10-fold, exhibits anticonvulsant properties in animal models of epilepsy.
PC-49471

MO-I-1100

ASPH inhibitor

MO-I-1100 is a small molecule inhibitor of aspartyl-(asparaginyl)-β-hydroxylase (ASPH), inhibits the β-hydroxylase activity of ASPH about 80%, inhibits Notch signaling in HCC cancer cells.
PC-49272

CRS0540

PolC inhibitor

CRS0540 is a potent, selective PolC DNA polymerase inhibitor that has demonstrated good in vitro and in vivo activity against Listeria monocytogenes.
PC-49154

AG17724

Pin1 inhibitor

AG17724 (Pin1 inhibitor DMS) is a selective inhibitor of prolyl isomerase Pin1 with Ki of 0.03 uM, DMS functionalized with CAF-targeting anti-FAP-α antibodies (antiCAFs-DMS) can selectively inhibit Pin1 in CAFs, leading to efficacious but transient tumor growth inhibition.
PC-47049

IPHBA

IL-31 inhibitor

IPHBA is a small-molecule inhibitor that suppresses EPAS1-driven IL-31 induction, selectively inhibits TCR-mediated IL-31 induction in murine CD4+ T cells with IC50 of 10.6 uM.

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