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Swainsonine

Chemical Structure : Swainsonine

CAS No.: 72741-87-8

Swainsonine (Tridolgosir)

Catalog No.: PC-23192Not For Human Use, Lab Use Only.

Swainsonine (Tridolgosir) is a natural product indolizidine alkaloid and an inhibitor of the human Golgi α-mannosidase, hGMII (MAN2A1), induces apoptosis and cell cycle arrest at G2/M phase, shows anti-tumor activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Swainsonine (Tridolgosir) is a natural product indolizidine alkaloid and an inhibitor of the human Golgi α-mannosidase, hGMII (MAN2A1), induces apoptosis and cell cycle arrest at G2/M phase, shows anti-tumor activity.

Physicochemical Properties

M.Wt 173.21
Formula C8H15NO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,2,8-Indolizinetriol, octahydro-, (1S,2R,8R,8aR)-

References

1. Koemans T, Chem Commun (Camb). 2024 Sep 25.

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