CDD-3290 | PSA inhibitor | Probechem Biochemicals

Chemical Structure : CDD-3290

CDD-3290 (CDD3290)

Catalog No.: PC-23067Not For Human Use, Lab Use Only.

CDD-3290 is a specific small molecule inhibitor of prostate-specific antigen (PSA; KLK3) with Ki of 216 nM.

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Biological Activity

CDD-3290 is a specific small molecule inhibitor of prostate-specific antigen (PSA; KLK3) with Ki of 216 nM.
CDD-3290 shows minimal inhibitory activity against elastase (Ki = 1.18 mM) and is 12.7-fold less potent against α-chymotrypsin (Ki = 2.74 μM).
CDD-3290l exhibits similar inhibition against thrombin (Ki = 0.411 μM).

Physicochemical Properties

M.Wt	334.34
Formula	C17H14N6O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(5-amino-3-(6-methoxypyridin-3-yl)-1H-pyrazol-1-yl)(1H-benzo[d]imidazol-5-yl)methanone

References

1. Erickson JA, et al. ACS Med Chem Lett. 2024 Aug 5;15(9):1526-1532.

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CDD-3290 (CDD3290)

Biological Activity

Physicochemical Properties

References

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