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GSD-16-24

Chemical Structure : GSD-16-24

CAS No.:

GSD-16-24

Catalog No.: PC-23153Not For Human Use, Lab Use Only.

GSD-16-24 is a small molecule inhibitor of amyloid fibrils of α-synuclein (α-syn), binds directly to the C-terminal IDR of α-syn monomer and fibril, preventing the fibril from binding to the receptors.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GSD-16-24 is a small molecule inhibitor of amyloid fibrils of α-synuclein (α-syn), binds directly to the C-terminal IDR of α-syn monomer and fibril, preventing the fibril from binding to the receptors.

Physicochemical Properties

M.Wt 434.50
Formula C24H26N4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(6-(4-methylpiperazin-1-yl)naphthalen-2-yl)methyl (3-(hydroxycarbamoyl)phenyl)carbamate

References

1. Zhang S, et al. J Am Chem Soc. 2024 Sep 27. doi: 10.1021/jacs.4c08869.

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