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Chemical Structure : FUT8 Inhibitor 40
Catalog No.: PC-23122Not For Human Use, Lab Use Only.
FUT8 Inhibitor 40 is a selective, cell-active inhibitor of α-1,6-fucosyltransferase (FUT8), inhibits FUT8 without inhibiting other FUTs.
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FUT8 Inhibitor 40 is a selective, cell-active inhibitor of α-1,6-fucosyltransferase (FUT8), inhibits FUT8 without inhibiting other FUTs.
FUT8 Inhibitor 40 (20 uM) significantly inhibited FUT8 activity in a cell-based assay, suppressed phosphorylation of EGFR in HepG2 hepatoma cells.
FUT8 Inhibitor 40 suppresses T-cell inflammatory responses, indicating a potential use as an immunomodulator.
| M.Wt | 529.08 | |
| Formula | C32H33ClN2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Manabe Y, et al. Angew Chem Int Ed Engl. 2024 Sep 28:e202414682.
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