Azalanstat | HO-1 inhibitor | Probechem Biochemicals

Chemical Structure : Azalanstat

Azalanstat (RS-21607, RS21607)

Catalog No.: PC-23068Not For Human Use, Lab Use Only.

Azalanstat (RS-21607) is a selective cytochrome P450 enzyme lanosterol 14 alpha-demethylase cytochrome P450 enzyme lanosterol 14 alpha-demethylase (LDM), inhibits heme oxygenase 1 (HO-1, IC50=5.3 uM), shows cholesterol-lowering activity.

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Biological Activity

Physicochemical Properties

M.Wt	429.96
Formula	C22H24ClN3O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[[(2S,4S)-2-[2-(4-chlorophenyl)ethyl]-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methylsulfanyl]aniline

References

1. Walker KA, et al. J Med Chem. 1993 Jul 23;36(15):2235-7.

2. Burton PM, et al. Biochem Pharmacol. 1995 Aug 8;50(4):529-44.

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Azalanstat (RS-21607, RS21607)

Biological Activity

Physicochemical Properties

References

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