| Cat. No. |
Product Name |
Information |
| PC-20554 |
YQ456
Myoferlin inhibitor
|
YQ456 (YQ-456) is a specific small molecule inhibitor of Myoferlin (MYOF) with high binding affinity (KD=37 nM) to MYOF‐C2D domain, suppresses colorectal cancer invasion in vitro with IC50 of 110 nM. |
| PC-49766 |
CNS-11
Alpha-synuclein inhibitor
|
CNS-11 is a small molecules capable of disassembling preformed alpha-synuclein fibrils, may exert it's disaggregating effects on the N terminus of the fibril core. |
| PC-49726 |
Seletracetam
SV2A ligand
|
Seletracetam (ucb 44212) is a high affinity for the synaptic vesicle protein 2A (SV2A) than levetiracetam with 10-fold, exhibits anticonvulsant properties in animal models of epilepsy. |
| PC-49471 |
MO-I-1100
ASPH inhibitor
|
MO-I-1100 is a small molecule inhibitor of aspartyl-(asparaginyl)-β-hydroxylase (ASPH), inhibits the β-hydroxylase activity of ASPH about 80%, inhibits Notch signaling in HCC cancer cells. |
| PC-49272 |
CRS0540
PolC inhibitor
|
CRS0540 is a potent, selective PolC DNA polymerase inhibitor that has demonstrated good in vitro and in vivo activity against Listeria monocytogenes. |
| PC-49154 |
AG17724
Pin1 inhibitor
|
AG17724 (Pin1 inhibitor DMS) is a selective inhibitor of prolyl isomerase Pin1 with Ki of 0.03 uM, DMS functionalized with CAF-targeting anti-FAP-α antibodies (antiCAFs-DMS) can selectively inhibit Pin1 in CAFs, leading to efficacious but transient tumor growth inhibition. |
| PC-38655 |
ELOVL1-IN-27
ELOVL1 inhibitor
|
ELOVL1-IN-27 is a highly potent, selective, CNS-penetrant inhibitor of elongation of very long chain fatty acid 1 enzyme (ELOVL1) with IC50 of 13 nM (C26:0 VLCFA inhibition in HEK cell). |
| PC-38598 |
Azo-resveratrol
Tyrosinase inhibitor
|
Azo-resveratrol is a potent mushroom tyrosinase inhibitor with IC50 of 36.28 uM. |
| PC-38531 |
ML266
GCase chaperone
|
ML266 (CID 46943215) is a non-inhibitory chaperone of glucocerebrosidase (GCase) enzyme, does not inhibit the enzyme’s action, but can facilitate its translocation to the lysosome. |
| PC-73312 |
FQI2
LSF inhibitor
|
Factor quinolinone inhibitor 2 (FQI2) is a small molecule inhibitor of transcription factor LSF, inhibits LSF DNA-binding activity both in vitro and in cells (IC50=0.71 uM). |
| PC-73176 |
PPA904
Photosensitizer
|
PPA-904 is a specific phenothiazine photosensitizer in photodynamic therapy (PDT) research, especially topical application for cutaneous leishmaniasis in vivo. |
| PC-73160 |
ALC-0315
Vaccine adjuvant
|
ALC-0315 is a synthetic ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles, has attracted attention as a component of the SARS-CoV-2 vaccine. |
