Chemical Structure : Leflunomide
CAS No.: 75706-12-6
Catalog No.: PC-22222Not For Human Use, Lab Use Only.
Leflunomide is a potent dihydroorotate dehydrogenase (DHODH) and pyrimidine synthesis inhibitor with IC50 of 208.5 nM in cell-free human DHODH enzyme inhibition assays.
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Leflunomide is a potent dihydroorotate dehydrogenase (DHODH) and pyrimidine synthesis inhibitor with IC50 of 208.5 nM in cell-free human DHODH enzyme inhibition assays.
M.Wt | 270.21 | |
Formula | C12H9F3N2O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-Methyl-N-(4-(trifluoromethyl)phenyl)isoxazole-4-carboxamide |
1. Ola A Elgamal, et al. JCI Insight. 2024 Apr 22;9(8):e173646.
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