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MTOB sodium

Chemical Structure : MTOB sodium

CAS No.: 51828-97-8

MTOB sodium

Catalog No.: PC-22299Not For Human Use, Lab Use Only.

MTOB sodium is a potent C-terminal binding protein (CtBP) inhibitor, inhibits the transactivation activity of CtBP1 and CtBP2.

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Biological Activity

MTOB sodium is a potent C-terminal binding protein (CtBP) inhibitor, inhibits the transactivation activity of CtBP1 and CtBP2.
MTOB sodium (10 mM) causes significant derepression of 40% of CtBP target genes (including FGF9, CTNNB1, CEBPB, et al.) in MCF-7 and in MBA-MD-231 cfells.
MTOB sodium attenuates repetitive head injury-elicited neurologic dysfunction and neuroinflammation.

Physicochemical Properties

M.Wt 170.16
Formula C5H7NaO3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Methylthio-2-oxobutanoicacidsodiumsalt

References

1. Li H, et al. Int J Biol Sci. 2020 Feb 4;16(7):1107-1120.

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