| Cat. No. |
Product Name |
Information |
| PC-38529 |
pythiDC
CP4H1 inhibitor
|
pythiDC is a small molecule inhibitor of human CP4H1 with IC50 of 4.0 uM, inhibits CP4H activity in cultured cells at concentrations that do not cause iron deficiency. |
| PC-38525 |
ML198
GCase chaperone
|
ML198 is a non-inhibitory chaperone of glucocerebrosidase (GCase) enzyme, does not inhibit the enzyme’s action, but can facilitate its translocation to the lysosome. |
| PC-38518 |
MSBN
|
MSBN is a highly selective fluorogenic probe for thiols, selectively imaging thiols in live cells and specifically label protein thiols with a turn-on signal to determine diverse reversible protein thiol modifications. |
| PC-38516 |
GSK106
PAD4 inhibitor
|
GSK106 is an inactive control for the selective PAD4 inhibitors, GSK484 and GSK199. |
| PC-38515 |
Creatine riboside
|
Creatine riboside is a metabolite standard and classifier of lung cancer status in all and stage I–II cases, important for early detection, and also associated with worse prognosis in stage I–II lung cancer. |
| PC-38501 |
MrgX1 modulator 8e
MrgX1 modulator
|
MrgX1 inhibitor 8e is a potent, allosteric modulator of MrgX1 with EC50 of 13 nM, shows improved potency and microsomal stability than ML382. |
| PC-38497 |
UNC7467
IP6K inhibitor
|
UNC7467 is a potent, selective inositol hexakisphosphate kinase (IP6K) inhibitor with IC50 values of 8.9 nM (IP6K1), 4.9 nM (IP6K2) and 1320 nM (IP6K3). |
| PC-38482 |
CYM2503
GalR2 PAM
|
CYM2503 is a putative galanin receptors type 2 (GalR2) positive allosteric modulator, concentration-dependently potentiates galanin (100 nM) stimulated IP1 accumulation in HEK293-GalR2 cells with EC50 of 0.69 uM, efficacy of 9.7-fold potentiation. |
| PC-38478 |
KYP-2047
Prolyl oligopeptidase (PREP) inhibitor
|
KYP-2047 is a high affinity prolyl oligopeptidase (PREP) inhibitor with Ki of 0.023 nM, reduces α-synuclein protein levels and aggregates in cellular and animal models of PD. |
| PC-38445 |
ML180
LRH1 (NR5A2) inhibitor
|
ML180 (SR1848) is a potent, selective Liver Receptor Homologue-1 (LRH1, NR5A2) inverse agonist with IC50 of 3.7 uM in reporter assays, displays no activity against SF1 (NR5A1). |
| PC-38444 |
ML179
LRH1 (NR5A2) inhibitor
|
ML179 (SR1309) is a potent, selective Liver Receptor Homologue-1 (LRH1, NR5A2) inverse agonist with IC50 of 320 nM in reporter assays, displays no activity against SF1 (NR5A1). |
| PC-38436 |
NEK7 inhibitor M12
NEK7 inhibitor
|
NEK7 inhibitor M12 is a novel potent inhibitor of NEK7 protein, inhibits cell viability of human HepG2 liver cancer cells. |
