| Cat. No. |
Product Name |
Information |
| PC-21430 |
WDR91-IN-1
WDR91 inhibitor
|
WDR91-IN-1 is a small molecule ligand of WD40 repeat-containing protein 91 (WDR91) with SPR KD value of 6 uM. |
| PC-21429 |
Dp44mT
Iron chelator
|
Dp44mT is an iron chelator with selective anticancer activity, exhibits wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics. |
| PC-21417 |
HQY436
CPSF3 inhibitor
|
HQY436 is a specific, orally bioavailable inhibitor of pre-messenger RNA endonuclease cleavage and polyadenylation specificity factor 3 (CPSF3) with binding IC50 of 0.15 uM, exhibits potent antitumor activity. |
| PC-21411 |
AE1 inhibitor 22
Anion exchanger 1 inhibitor
|
AE1 inhibitor 22 is a small molecule inhibitor of the anion exchanger 1 transporter (AE1) with IC50 of 18 uM. |
| PC-21410 |
LY3522348
Ketohexokinase (KHK) inhibitor
|
LY3522348 is a potent, highly selective, oral dual inhibitor of human ketohexokinase isoforms C and A (hKHK-C, hKHK-A) with IC50 of 20 nM and 24 nM, respectively. |
| PC-21409 |
ECF inhibitor 1
ECF transporter inhibitor
|
ECF inhibitor 1 is a specific small molecule inhibitor of energy-coupling factor (ECF) transporters, potentially acting as protein-protein interaction (PPI) modulator. |
| PC-21391 |
IMB0901
Myostatin inhibitor
|
IMB0901 is a small molecule myostatin (MSTN) inhibitor that inhibits the MSTN promoter activity, the MSTN signaling pathway, and the MSTN positive feedback regulation. |
| PC-21383 |
IBS007125
c-Maf inhibitor
|
IBS007125 is a small molecule inhibitor of c-Maf, inhibits multiple myeloma proliferation by targeting cMaf transcriptional activity. |
| PC-21381 |
Mitoquinone mesylate
TRAP1 inhibitor
|
Mitoquinone mesylate (MitoQ) is a potent inhibitor of TRAP1 activity in cancer cells with IC50 of 0.2 uM in 22Rv1 cells, reduces SDHB and SIRT3 and increases phosphor-AMPK and CHOP. |
| PC-21378 |
B3GNT2 inhibitor 8j
B3GNT2 inhibitor
|
B3GNT2 inhibitor 8j is a potent, seletive and orally active inhibitor of β-1,3-N-Acetylglucosaminyltransferase 2 (B3GNT2) with IC50 of 9 nM, shows no activity against B3GNT2 (IC50>250 uM). |
| PC-21373 |
UTBinh-14
Urea transporter UT-B inhibitor
|
UTBinh-14 is a potent, highly selective inhibitor for urea transporter UT-B with IC50 of 11 nM, with over a thousand-fold selectivity over UT-A. |
| PC-21360 |
Heparanase-1 inhibitor 18
Heparanase-1 inhibitor
|
Heparanase-1 inhibitor 18 is a potent, selective inhibitor of heparanase-1 (HPSE1) with IC50 of 442 nM. |
