| Cat. No. |
Product Name |
Information |
| PC-43424 |
NXY-059
|
NXY-059 (Disufenton sodium) is a free radical-trapping agent that demonstrates a considerable neuroprotective effect in vivo. |
| PC-43398 |
Avasimibe
ACAT inhibitor
|
Avasimibe (CI-1011, PD-148515) is a potent, selective inhibitor of acyl-CoA: cholesterol O-acyl transferase (ACAT) with IC50 of 60 nM. |
| PC-43358 |
SMND-309
|
SMND-309 is a derivate of salvianolic acid B, attenuates apoptosis and ameliorates mitochondrial energy metabolism in rat cortical neurons. |
| PC-43319 |
Laquinimod
Immunoregulator
|
Laquinimod (ABR-215062) is an immunoregulator derived from Linomide, has been shown to completely inhibit the development of murine acute experimental autoimmune encephalomyelitis (EAE). |
| PC-43315 |
D-Fagomine
Glycosidase inhibitor
|
D-Fagomine (Fagomine) is a a mild glycosidase inhibitor, inhibits Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast) with Ki of 4.8 uM, 39 uM, and 70 uM, respectively. |
| PC-43253 |
KHK-IN-8 hydrochloride
Ketohexokinase inhibitor
|
KHK-IN-8 hydrochloride is a potent ketohexokinase (KHK) inhibitor with IC50 of 12 nM, interacts with Asp-27B in the ATP-binding region of KHK, also shows potent cellular KHK inhibition with IC50 of <500 nM. |
| PC-43252 |
KHK-IN-8
Ketohexokinase inhibitor
|
KHK-IN-8 is a potent ketohexokinase (KHK) inhibitor with IC50 of 12 nM, interacts with Asp-27B in the ATP-binding region of KHK, also shows potent cellular KHK inhibition with IC50 of <500 nM. |
| PC-43251 |
OBA-09
|
OBA-09 is a simple ester of pyruvate and salicylic acid, main metabolites of pyruvate and aspirin, respectively, exerts robust neuroprotective effect in the postischemic brain in vivo. |
| PC-43248 |
EN460
ERO1 inhibitor
|
EN460 is a specific mall molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1), interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation (IC50=1.9 uM). |
| PC-43242 |
AMZ30
PME-1 inhibitor
|
AMZ30 is a potent, selective, covalent inhibitor of the serine hydrolase protein phosphatase methylesterase-1 (PME-1) with IC50 of 0.6 uM, >100-fold selectivity over other SHs. |
| PC-43236 |
Sortin1
Sorting inhibitor
|
Sortin1 is a small molecule sorting inhibitor (Sortin) that induces reversible defects in vacuole biogenesis and root development in Arabidopsis seedlings at 100 mg/liter (227 uM). |
| PC-43231 |
AEBSF
Serine protease inhibitor
|
AEBSF is an irreversible serine protease inhibitor that inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. |
