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Cat. No. Product Name Information
PC-43170

Genz-123346 free base

Glucosylceramide synthase inhibitor

Genz-123346 is a potent, specific glucosylceramide synthase inhibitor with IC50 of 14 nM (GM1 inhibition), does not inhibit α-glucosidase or glucocerebrosidase and little effect on 1-O-acylceramide synthase activity.
PC-43150

Succinyl phosphonate

KGDHC inhibitor

Succinyl phosphonate is an α-Ketoglutarate phosphoanalogue, α-ketoglutarate dehydrogenase inhibitor, effectively inhibits α-ketoglutarate oxidative decarboxylation.
PC-63231

TJ191

TJ191 is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells (MOLT-3 IC50=0.26 uM).
PC-63220

VUT-MK142

Cardiomyogenic agent

VUT-MK142 is a cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes, shows superior cardiomyogenic activity over cardiogenol C.
PC-63195

RCGD 423

gp130 modulator

RCGD 423 (RCGD423) is a small molecule gp130 modulator that prevents articular cartilage degeneration and promotes repair both in vitro and in vivo.
PC-43111

Thiamet G

O-GlcNAcase inhibitor

Thiamet-G is a potent, selective O-GlcNAcase inhibitor with Ki of 21 nM for human O-GlcNAcase, blocks phosphorylation of tau both in vitro and in vivo.
PC-43102

Sermorelin

GHRH analog

Sermorelin (GHRH (1-29)) is a peptide analogue of growth hormone-releasing hormone (GHRH) which is used as a diagnostic agent to assess growth hormone (GH) secretion for the purpose of diagnosing growth hormone deficiency.
PC-42996

FH1

FH1 (BRDK4477) is a small molecule that increase function and proliferation of primary human hepatocytes, promotes the differentiation of iPS-derived hepatocytes.
PC-42932

XEN445

Endothelial lipase inhibitor

XEN445 is a potent, selective endothelial lipase (EL) inhibitor with IC50 of 237 nM, displays no significant activity against lipoprotein lipase (LPL) and hepatic lipase (HL) (IC50=20 and 9.5 uM).
PC-42915

PFK15

PFKFB3 inhibitor

PFK15 (PFK 015) is a potent, selective 6-phosphofructo-2-kinase (PFKFB3) inhibitor with IC50 of 207 nM against recombinant human PFKFB3, displays 100-fold more activity than 3PO.
PC-42360

γ-Glu-Phe

γ-Glu-Phe (γ-Glutamylphenylalanine) is a γ-glutamyl dipeptide..
PC-42359

Coproporphyrin III

Coproporphyrin III is a diffusible small molecule porphyrin excreted by human-associated Propionibacterium spp., induces Staphylococcus aureus aggregation and biofilm formation, also induces S. aureus to form a plasma-independent surface-attached biofilm.

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