| Cat. No. |
Product Name |
Information |
| PC-20764 |
SW088799
Glucagon release inhibitor
|
SW088799 is a small molecule glucagon release inhibitor with IC50 of 1.26 uM, with minimal impact on insulin release. |
| PC-20754 |
BACH1 inhibitor M2
Bach1 inhibitor
|
BACH1 inhibitor M2 is a small molecule inhibitor of the transcription factor BTB and CNC homolog 1 (BACH1), inhibits AFB1-induced porcine and human cell death in vitro and AFB1-induced symptoms of weight loss and liver injury in vivo. |
| PC-20751 |
FSHR agonist 21f
FSHR agonist
|
FSHR agonist 21f is a small molecule allosteric agonist of follicle stimulating hormone receptor (FSHR) with high affinity and activation efficacy (pEC50=7.72). |
| PC-20750 |
TOP5300
FSHR agonist
|
TOP5300 (TOP05300) is a potent, selective, orally active allosteric agonist of follicle stimulating hormone receptor (FSHR) with EC50 of 9.72 nM, 80-fold selectivity over hLHR. |
| PC-20749 |
TOP5668
FSHR agonist
|
TOP5668 (TOP05668) is a potent, selective, orally active allosteric agonist of follicle stimulating hormone receptor (FSHR) with EC50 of 2.2 nM, 80-fold selectivity over hLHR. |
| PC-20748 |
Org 214444-0
FSHR agonist
|
Org 214444-0 is a highly potent, selective, allosteric agonist of follicle stimulating hormone receptor (FSHR) with EC50 of 2.0/1.2 nM (human/rat FSHR) in cell-based assays. |
| PC-20736 |
F759
Cyclophilin inhibitor
|
F759 is a nonpeptidic small-molecule cyclophilin inhibitor, inhibits coagulation induced by procoagulant platelets. |
| PC-20735 |
F83236
Cyclophilin inhibitor
|
F83236 is a nonpeptidic small-molecule cyclophilin inhibitor, inhibits coagulation induced by procoagulant platelets. |
| PC-20719 |
A1120
RBP4 inhibitor
|
A1120 is a high affinity, non-retinoid ligand for retinol-binding protein 4 (RBP4) with Ki of 8.3 nM, disrupts the interaction between RBP4 and its binding partner transthyretin (TTR). |
| PC-20718 |
BPN-14136
RBP4 inhibitor
|
BPN-14136 is a potent, selective and non-retinoid RBP4 antagonist with SPA IC50 of 12.8 nM and HTRF IC50 of 43.6 nM. |
| PC-20717 |
RBP4 antagonist 59
RBP4 inhibitor
|
RBP4 antagonist 59 is a potent, selective and orally bioavailable retinol-binding protein 4 (RBP4) antagonist with HTRF IC50 of 16 nM. |
| PC-20714 |
ME-143
ENOX2 inhibitor
|
ME-143 (NV-143) is a second-generation tumor-specific NADH oxidase inhibitor, binds to purified recombinant ENOX2 with Kd value of 43 nM, shows broad activity against human cancers in vitro and in vivo. |
