Cat. No. |
Product Name |
Information |
PC-61794 |
Sodium cromoglicate
|
Sodium cromoglicate is a mast cell stabilizer with anti-inflammatory activity that prevents the release of inflammatory chemicals such as histamine, leukotrienes from mast cells. |
PC-61730 |
OX-14
|
OX-14 is a highly potent farnesyl pyrophosphate synthase (FPPS) inhibitor with IC50 of 2.46 nM, with significantly lower binding affinity to hydroxyapatite. |
PC-61689 |
Fhit-IN-15
|
Fhit-IN-15 is a potent, competitive, reversible inhibitor of the enzymatic activity of tumor suppressor Fhit with IC50 of 49 nM, shows cytotoxicity in HEK293T cells.. |
PC-61683 |
Juglone
|
Juglone (5-HN) is a plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities. |
PC-61655 |
Chromeceptin
|
A cell-permeable benzochromene that selectively impairs the viability and growth of IGF2-overexpressing hepatocellular carcinoma cells, binds to MFP-2, stimulates the expression of IGFBP-1 and SOCS-3 through activation of STAT6. |
PC-61519 |
NPD926
|
A small molecule ROS inducer that induces rapid cell death in cancer cells, induces reactive oxygen species via cellular glutathione depletion. |
PC-61472 |
PXS-4681A
|
A potent, selective, and irreversible inhibitor of SSAO/VAP-1 (AOC3) with Ki of 37 nM, IC50 of <10 nM. |
PC-61429 |
Lucerastat
|
A galactose analogue that is an UDP-glucose ceramide glucosyltransferase (UGCG/GCS) inhibitor (IC50=41.4 uM). |
PC-61426 |
CCG-203586
|
A potent, CNS-active Glucosylceramide synthase (GCS) inhibitor with IC50 of 27 nM. |
PC-61425 |
PDMP hydrochloride
|
A ceramide analog that inhibits glucosylceramide synthase (GCS), reduces the synthesis of sphingosine and its derivatives, increases cellular ceramide, and induces cell cycle arrest. . |
PC-61424 |
Fumonisin B1
|
A mycotoxin produced from F. moniliforme, and an inhibitor of ceramide synthase (sphingosine N-acyltransferase/CerS). |
PC-61401 |
Tepilamide fumarate
|
A small-molecule, fumaric acid ester (FAE) compound that is a prodrug of methyl hydrogen fumarate (also known as monomethyl fumarate), for the treatment of relapsing-remitting multiple sclerosis and plaque psoriasis.. |