| Cat. No. |
Product Name |
Information |
| PC-21231 |
Glutamate-cysteine ligase inhibitor EN25
Glutamate-cysteine ligase inhibitor
|
Glutamate-cysteine ligase inhibitor EN25 is a covalent inhibitor of the glutamate-cysteine ligase (GCL) with IC50 of 16 uM, targets an allosteric cysteine C114 on GCLM, the modifier subunit of GCL. |
| PC-21228 |
LX-6171
Proline transporter inhibitor
|
LX-6171 is a small molecule proline transporter (SLC6A7) inhibitor with potential for treating cognitive and other disorders. |
| PC-21227 |
LP-403812
Proline transporter inhibitor
|
LP-403812 is a specific small molecule inhibitor of mammalian proline transporter (PROT), inhibits PROT-mediated proline uptake with IC50 of 0.1 uM on both recombinant human and mouse PROT. |
| PC-21217 |
O-1918
GPR18 antagonist
|
O-1918 is a selective, potent antagonist of non-canonical cannabinoid GPR18, does not bind to CB(1) or CB(2) receptors and does not cause vasorelaxation at concentrations up to 30 uM. |
| PC-21214 |
GPR61 inverse agonist compound 1
GPR61 inverse agonist
|
GPR61 inverse agonist compound 1 is a potent and selective GPR61 inverse agonist with functional IC50 of 10-11 nM in cAMP assays. |
| PC-21207 |
Ticlopidine
CD39 inhibitor
|
Ticlopidine (PCR 5332) is an allosteric, noncompetitive inhibitor of CD39 with the IC50 of 81.7 μM, shows antithrombotic effect. |
| PC-21205 |
ARL67156
ecto-ATPase inhibitor
|
ARL67156 (FPL 67156) is a selective inhibitor of ecto-ATPase, ARL67156 is a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively. |
| PC-21193 |
Gliotoxin
LTA4 hydrolase inhibitor
|
Gliotoxin (Aspergillin) is a virulence factor of Aspergillus fumigatus, functions as a potent and selective inhibitor of the epoxide hydrolase activity of LTA4 hydrolase (LTA4H), selectively inhibits LTB4 biosynthesis. |
| PC-21176 |
GPR54 antagonist 9l
GPR54 inhibitor
|
GPR54 antagonist 9l is a potent, selective, small molecule antagonist of GPR54 with IC50 of 3.7 nM (human GPR54) in receptor binding assays. |
| PC-21175 |
GPR54 antagonist 15a
GPR54 inhibitor
|
GPR54 antagonist 15a is a potent, selective, small molecule antagonist of GPR54 with IC50 of 3.6/15 nM (human/rat GPR54) in receptor binding assays. |
| PC-21174 |
KISS1R antagonist P234
GPR54 inhibitor
|
KISS1R antagonist P234 (GPR54 antagonist P234, Peptide P234) is a potent GPR54 receptor antagonist with binding IC50 of 2.7 nM in competition with 125I-kisspeptin-10, blocks the stimulatory effects of kisspeptin on hypothalamus-pituitary-gonadal (HPG) axis. |
| PC-21150 |
ST2 inhibitor XY52
ST2 inhibitor
|
ST2 inhibitor XY52 is a specific small molecule inhibitor of soluble suppression of tumorigenesis-2 factor (ST2) with IC5 of 5.68 and 4.59 uM in ST2/IL-33 AlphaLISA and HEK-Blue reporter assays, repsectively. |
