MASTL inhibitor 16

Chemical Structure : MASTL inhibitor 16

Catalog No.: PC-23351Not For Human Use, Lab Use Only.

MASTL inhibitor 16 is a potent, highly selective inhibitor of microtubule-associated serine/threonine kinase-like (MASTL, Greatwall) with Ki of 0.12 nM, cellular pENSA IC50 of 2.8 nM in MDA-MB-231 cells.

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Biological Activity

Physicochemical Properties

M.Wt	421.51
Formula	C22H27N7O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(6-((8-amino-6-methyl-2,7-naphthyridin-3-yl)amino)-4-(3-aminopentan-3-yl)pyridin-2-yl)oxazolidin-2-one

References

1. Gallego RA, et al. J Med Chem. 2024 Nov 5. doi: 10.1021/acs.jmedchem.4c01659.

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MASTL inhibitor 16

Biological Activity

Physicochemical Properties

References

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