You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets

Request The Product List ofOther Targets Other Targets

Cat. No. Product Name Information
PC-38711

TFF3 inhibitor AMPC

TFF3 inhibitor

AMPC is a first-in-class small-molecule inhibitor of the oncogenic functions of trefoil factor 3 (TFF3) that specifically monomerizes dimeric TFF3 to inhibit dimeric TFF3 function, specifically binds to Cys57 of TFF3.
PC-38705

AF615

CDT1/Geminin inhibitor

AF615 is a potent and selective small-molecule inhibitor targeting the CDT1/Geminin protein complex with Ki of 0.37 uM aginst Geminin-tCDT1 interaction, inhibits inhibit Geminin/CDT1 complex formation in vitro with IC50 of 0.313 uM.
PC-38700

ALKBH5 inhibitor 20m

ALKBH5 inhibitor

ALKBH5 inhibitor 20m is a potent, selective RNA m6A demethylase AlkB homolog 5 (ALKBH5) inhibitor with IC50 of 21 nM.
PC-38697

PAANIB-1

PAAN/MIF nuclease inhibitor

PAANIB-1 is a brain-penetrant PAAN/MIF nuclease inhibitor that prevents neurodegeneration that prevents neurodegeneration induced by α-syn PFF, AAV-α-syn overexpression, or MPTP intoxication in vivo.
PC-38675

Ninerafaxstat trihydrochloride

Ninerafaxstat (CV-8972) is a small molecule compound that promotes glucose oxidation, decreases fatty acid oxidation and improve overall mitochondrial respiration, inhibits the growth and proliferation of cancer cells.
PC-38674

Ninerafaxstat

Ninerafaxstat (CV-8972) is a small molecule compound that promotes glucose oxidation, decreases fatty acid oxidation and improve overall mitochondrial respiration, inhibits the growth and proliferation of cancer cells.
PC-38668

JHU395

Glutamine antagonist

JHU395 is orally-bioavailable glutamine antagonist prodrug, shows antitumor activity in malignant peripheral nerve sheath tumor (MPNST, sNF96.2 cell growth IC50=4.6 uM).
PC-38667

(S)-IBD3540

GCPII inhibitor

(S)-IBD3540 is a potent, gut-restricted and orally active small molecule glutamate carboxypeptidase II (GCPII) inhibitor with IC50 of 4 nM, demonstrates anti-colitis activity in both acute and chronic mouse colitis models.
PC-38658

DS69910557

hPTHR1 antagonist

DS69910557 is a highly potent, selective orally available human parathyroid hormone receptor 1 (hPTHR1) antagonist with IC50 of 0.08 uM.
PC-38651

TLK1 inhibitor J54

TLK1 inhibitor

TLK1 inhibitor J54 (J3-54) is a potent, small-molecule TLK1 inhibitor, induces apoptosis in AS PCa cells, suppresses growth of LNCaP xenografts combined with bicalutamide.
PC-38631

SFI003

SRSF3 inhibitor

SFI003 is novel serine/arginine-rich splicing factor 3 (SRSF3) inhibitor, inhibits the proliferation and migration of CRC cells, inhibits the proliferation of HCT-116 with IC50 of 8.78 uM.
PC-38630

PEPCKi

PEPCK inhibitor

PEPCKi is a small molecule inhibitor of hosphoenolpyruvate carboxykinase (PEPCK), blocks lactate utilization and impairs tumor growth in colorectal cancer.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com