| Cat. No. |
Product Name |
Information |
| PC-47060 |
GNF-9228
β-cell proliferation activator
|
GNF-9228 is a small molecule that stimulates human β-cell proliferation, selectively activates human β-cell relative to α- or δ-cell proliferation. |
| PC-47057 |
MK-0159
CD38 inhibitor
|
MK-0159 is a highly potent, orally bioavailable CD38 enzymatic inhibitor with IC50 of 3 nM (murine CD38) in in vitro assays. |
| PC-47056 |
ZY-444
Pyruvate carboxylase inhibitor
|
ZY-444 is a specific metabolic inhibitor of pyruvate carboxylase, a key anaplerotic enzyme of the tricarboxylic acid cycle (TCA cycle), suppresses breast cancer growth and metastasis through inhibiting the Wnt/β‐catenin/Snail signaling pathway. |
| PC-47049 |
IPHBA
IL-31 inhibitor
|
IPHBA is a small-molecule inhibitor that suppresses EPAS1-driven IL-31 induction, selectively inhibits TCR-mediated IL-31 induction in murine CD4+ T cells with IC50 of 10.6 uM. |
| PC-47047 |
FeTPPS
|
FeTPPS is a ferric porphyrin complex that causes the decomposition of peroxynitrite by catalytic isomerization to produce nitrate both in vitro and in vivo. |
| PC-47039 |
GQ352
Gαq/11 inhibitor
|
GQ352 is a small molecule Gαq/11 inhibitor, directly binds to the Gαq and inhibits the dissociation of Gαβγ heterotrimers with IC50 value of 8.9 uM. |
| PC-47038 |
SP-8008
SIPA inhibitor
|
SP-8008 (PCA-8008) is a potent, selective inhibitor of shear stress-induced platelet aggregation (SIPA) with IC50 of 1.44 uM, effectively and broadly blocks SIPA events and attenuates platelet activation and aggregation. |
| PC-38907 |
2-TCPA
CAD inhibitor
|
2-TCPA is a potent, specific inhibitor of carbamoyl-phosphate synthetase, aspartate transcarbamoylase, and dihydroorotase (CAD), suppresses SARS-CoV-2 replication in Caco-2 cells with IC50 of 2.36 uM. |
| PC-38905 |
(R)-HTS-3
LPCAT3 inhibitor
|
(R)-HTS-3 is a small-molecule inhibitor of lysophosphatidylcholine acyltransferase 3 (LPCAT3) with IC50 of 0.09 uM, an integral membrane acyltransferase in the Lands cycle responsible for generating C20:4 phospholipids. |
| PC-38904 |
CIB-3b
TRBP-Dicer inhibitor
|
CIB-3b is a small molecule inhibitor disrupting the TRBP-Dicer interaction, suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells. |
| PC-38900 |
XST-20
FOXM1 inhibitor
|
XST-20 is a small molecule selectively targeting FOXM1 DNA-binding domain (DBD) with SPR Kd of 20 uM, effectively suppresses FOXM1 transcriptional activities and inhibits ovarian cancer cell proliferation. |
| PC-38889 |
Alrefimotide
|
Alrefimotide (Telomerase reverse transcriptase 660-689 peptide antigen). |
