| Cat. No. |
Product Name |
Information |
| PC-27050 |
Commendamide
GPR132 agonist
|
Commendamide is natively produced by commensal Bacteroides and specific agonist of GPCR G2A/GPR132 with EC50 of 11.8 uM, attenuates skeletal muscle ferroptosis in vitro. |
| PC-27049 |
SB-583355
GPR132 antagonist
|
SB‐583355 isa potent, peptidomimetic inhibitor of GPR132 (G2A), inhibits agonist‐induced hGPR132aPL association with β‐arrestin with pIC50 of 7.0. |
| PC-27048 |
SB-583831
GPR132 agonist
|
SB-583831 is a potent, selective agonist of G‐protein‐coupled receptor GPR132 (G2A) with pEC50 of 7.7 and 7.3 in yeast and β‐arrestin assays (human GPR132a). |
| PC-26995 |
SIPI11594
MPC inhibitor
|
SIPI11594 is a small molecule mitochondrial pyruvate carrier (MPC) inhibitor, shows cellular lactate production-enhancing activity, significantly accelerates hair regrowth and anagen entry. |
| PC-26982 |
Zearalenone
Endocrine disruptor
|
Zearalenone (Mycotoxin F2, Toxin F2) is a potent endocrine disruptor that poses serious health risks through reproductive toxicity. |
| PC-26955 |
UCM-1336
ICMT inhibitor
|
UCM-1336 is a potent, selective isoprenylcysteine carboxylmethyltransferase (ICMT) inhibitor with IC50 of 2 uM. |
| PC-26951 |
AGPS-IN-1
AGPS inhibitor
|
AGPS-IN-1 (AGPS inhibitor 2i) is a small molecule inhibitor of alkylglyceronephosphate synthase (AGPS), decreases ether lipids, cell migration and survival, specifically impairs EMT through E-cadherine, Snail, Mmp2 modulation. |
| PC-26941 |
NCGC00138783 TFA
CD47/SIRPα inhibitor
|
NCGC00138783 TFA is a selective inhibitor targeting CD47/SIRPα axis with IC50 of 50 µM, directly blocks the interaction between CD47 and SIRPα. |
| PC-26940 |
NCGC00138783
CD47/SIRPα inhibitor
|
NCGC00138783 is a selective inhibitor targeting CD47/SIRPα axis with IC50 of 50 µM, directly blocks the interaction between CD47 and SIRPα. |
| PC-26939 |
NCGC00092410
GCase inhibitor
|
NCGC00092410 is a potent, selective and nonsugar glucocerebrosidase (GC, GCase) inhibitor with IC50 of 31 nM. |
| PC-26936 |
NCGC00685960
NNMT inhibitor
|
NCGC00685960 is a highly potent, specific Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50 of <10 nM, increases H3K27 trimethylation levels in ovarian cancer cells and inhibits α-SMA expression in NNMT-expressing ovarian fibroblasts, has potent antitumor activity. |
| PC-26933 |
β-actin inhibitor C25
β-actin inhibitor
|
β-actin inhibitor C25 is potent, selective and covalent inhibitor of beta-actin (β-actin), does not target α- or γ-actin, inhibits β-Actin polymerization to disrupt the actin cytoskeleton and lead to cell death in143B cells (IC50=15 nM), selectively and covalently binds to Cys272 in β-actin. |
