Cat. No. |
Product Name |
Information |
PC-62928 |
Buthionine Sulfoximine
|
Buthionine Sulfoximine (BSO) is a glutathione (GSH)-depleting reagent that inhibits gamma-glutamylcysteine synthetase, the enzyme required in the first step of glutathione synthesis. |
PC-62867 |
(-)-CXL017
|
(-)-CXL017 is a small molecule that has selective cytotoxicity toward MDR cancer cell lines in vitro, through inhibition of the sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) with IC50 of 13.5 uM. |
PC-62861 |
PNPLA4-IN-1
|
PNPLA4-IN-1 is a potent, selective, and irreversible PNPLA4 inhibitor with IC50 of 1.8 uM (separated membrane proteome fraction), shows in-cell inhibition of PNPLA4 with IC50 of 11.7 uM.. |
PC-62860 |
PF-6808472
|
PF-6808472 (XO44) is a sulfonyl fluoride chemical probe that covalently labels a broad swath of the intracellular kinome with high efficiency. |
PC-62824 |
CCG-232601
|
CCG-232601 is a potent (IC50=0.55 uM), orally bioavailable Rho/MKL1/SRF transcriptional pathway that target transcriptional factor MRTF. |
PC-62786 |
VU6001221
|
VU6001221 is a potent choline transporter (CHT) inhibitor with IC50 of 270 nM. |
PC-62785 |
ML352
|
ML352 (VU-0476201) is a potent, selective choline transporter (CHT) inhibitor with Ki of 92 nM. |
PC-62713 |
SGPL1-IN-28
|
SGPL1-IN-28 is a novel S1P lyase inhibitor with in vitro IC50 of 120 nM, cell IC50 of 230 nM.. |
PC-62692 |
PTGR2-IN-22
|
PTGR2-IN-22 is a potent PTGR2 ligand that inhibits 15-keto-PGE2 reductase activity with IC50 of 0.55 uM in HEK293T cells. |
PC-62657 |
Retro 1
|
Retro 1 is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface. |
PC-62656 |
C450-0730
|
C450-0730 is a potent LuxN antagonist that antagonizes LuxN-AI-1 binding with IC50 of 2.7 uM. |
PC-62651 |
MS-37452
|
MS-37452 is a small-molecule modulator of methyl-lysine binding for CBX7 chromodomain. |