| Cat. No. |
Product Name |
Information |
| PC-26904 |
ADGRL1 inhibitor compound 2
ADGRL1 inhibitor
|
ADGRL1 inhibitor compound 2 is a potential small molecule inhibitor of adhesion G protein-coupled receptor L1 (ADGRL1/Latrophilin-1), activates the GSK3β-STAT1 axis in CT26 cells in vitro, consistent with the knockdown of Adgrl1. |
| PC-26902 |
CPN-351 TFA
NMUR1 antagonist
|
CPN-351 TFA is a potent, selective pentapeptide antagonist of Neuromedin U Receptor 1 (NMUR1) with pA2 and KB values of 7.35 and 45 nM, respectively, selective over NMUR2 with 6.38 and 421 nM, respectively. |
| PC-26901 |
CPN-351
NMUR1 antagonist
|
CPN-351 is a potent, selective pentapeptide antagonist of Neuromedin U Receptor 1 (NMUR1) with pA2 and KB values of 7.35 and 45 nM, respectively, selective over NMUR2 with 6.38 and 421 nM, respectively. |
| PC-26890 |
Sinbaglustat
GCS/GBA2 inhibitor
|
Sinbaglustat (OGT2378) is an orally available, blood-brain barrier permeable dual inhibitor of glucosylceramide synthase (GCS) and non-lysosomal glucosyl ceramidase (GBA2), Sinbaglustat is 50‐fold more potent in inhibiting GBA2 than GCS. |
| PC-26885 |
Tetrahydrocurcumin
36062-04-1
|
Tetrahydrocurcumin (THC, LG0367) is a antioxidative metabolite of curcumin, inhibits radiation-induced lipid peroxidation in rat liver microsomes, also suppresses melanin content and tyrosinase activity. |
| PC-26882 |
SIH-002
ZMIZ1 inhibitor
|
SIH-002 is a specific small-molecule inhibitor of ZMIZ1 (Zinc finger MIZ domain-containing protein 1) with SPR KD of 0.16 uM. |
| PC-26881 |
SIH-001
ZMIZ1 inhibitor
|
SIH-001 is a specific small-molecule inhibitor of ZMIZ1 (Zinc finger MIZ domain-containing protein 1) with SPR KD of 0.498 uM. |
| PC-26874 |
A-3190
CD38 inhibitor
|
A-3190 is a potent, selective, brain-penetrant CD38 inhibitor with IC50 of 7.2 nM and 1.2 nM for human and mouse CD38 respectively. |
| PC-26873 |
A-8531
CD38 inhibitor
|
A-8531 is a potent, selective, peripheral CD38 inhibitor with IC50 of 0.4 nM and 3.6 nM for human and mouse CD38 respectively. |
| PC-26871 |
CPN-116
NMUR2 agonist
|
CPN-116 is a potent, speciofic peptidic agonist of human neuromedin U receptor type 2 (NMUR2) with EC50 of 6.4 nM in calcium mobilization assays, significantly suppresses body weight gain in mice. |
| PC-26870 |
CPN-267 TFA
NMUR1 agonist
|
CPN-267 TFA is a potent, selective peptidic neuromedin U receptor 1 (NMUR1) agonist with EC50 of 0.25 nM. |
| PC-26850 |
EBNA1-IN-SC7
EBNA1 inhibitor
|
EBNA1-IN-SC7 (Compound SC7) is a selective Epstein-Barr nuclear antigen 1 (EBNA1) inhibitor that interferes with EBNA1-DNA binding activity with IC50 of 23 uM, completely blocks transcriptional activation of EBNA1. |
