| Cat. No. |
Product Name |
Information |
| PC-25037 |
Crovozalpon
Z α1-antitrypsin inhibitor
|
Crovozalpon is a small molecule inhibitor of Z-α1-antitrypsin polymerization. |
| PC-25025 |
Rivasterat
Endothelial dysfunction blocker
|
Rivasterat (CU06-1004, Sac-1004) is a small molecule vascular leakage blocker and endothelial dysfunction blocker, inhibits endothelial hyperpermeability induced by VEGF, histamine and thrombin via stabilization of cortical actin ring and AJ proteins at the cell-cell junction. |
| PC-25014 |
MG-257
Galectin-3/TREM2 inhibitor
|
MG-257 is a small molecule ligand of galectin-3, impedes interaction between TREM2 and galectin-3 with IC50 of 91 nM in TR-FRET assays, attenuates TREM2 signaling. |
| PC-25011 |
YT-II-100
CPSF3 inhibitor
|
YT-II-100 is a novel small molecule inhibitor of Cleavage and Polyadenylation Specific Factor 3 (CPSF3), increases the global abundance of R-loops. |
| PC-25008 |
Veonetinib
Tyrosine kinase inhibitor
|
Veonetinib (Example 3) is an effective inhibitor of tyrosine kinase, exhibits IC50 values of 0.1 μM and 0.4 μM in A549 cells and LOVO cells, respectively. |
| PC-24973 |
Progerinin
Lamin A-Progerin inhibitor
|
Progerinin (SLC-D011) is a specific, small molecule binding inhibitor of lamin A and progerin, reduces progerin expression and improves aging phenotypes in vitro and in vivo HGPS models. |
| PC-24962 |
KL1333
NAD+ modulator, NQO1 substrate
|
KL1333 (Napazimone) is an orally available, small molecule NAD+ modulator, reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. |
| PC-24943 |
LCKLSL hydrochloride
ANXA2 inhibitor
|
LCKLSL hydrochloride (Leu-Cys-Lys-Leu-Ser-Leu) is a potent, specific hexapeptide competitive inhibitor of Annexin A2 (AnxA2), inhibits tissue plasminogen activator (tPA)-binding capacity with IC50 of 11 uM. |
| PC-24942 |
LCKLSL
ANXA2 inhibitor
|
LCKLSL (Leu-Cys-Lys-Leu-Ser-Leu) is a potent, specific hexapeptide competitive inhibitor of Annexin A2 (AnxA2), inhibits tissue plasminogen activator (tPA)-binding capacity with IC50 of 11 uM. |
| PC-24925 |
TLCK
Trypsin like protease inhibitor
|
TLCK (Tos-Lys-CH2Cl, N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride ) is a specific, irreversible and covalent inhibitor of serine protease trypsin, modifies His-57 and Ser-195 of trypsin-like proteases and blocks the active site. |
| PC-24924 |
Mesotrypsin inhibitor CP13
Mesotrypsin inhibitor
|
Mesotrypsin inhibitor CP13 is a selective, small molecule inhibitor of mesotrypsin with Ki of 47 uM, 4-fold selective over human trypsin 1 and trypsin 2. |
| PC-24909 |
LSN3374443
Lp(a) formation inhibitor
|
LSN3374443 is a potent, dimeric apolipoprotein(a) (apo(a)) binder and inhibitor of Lipoprotein(a) (Lp(a)) formation, disrupts the formation of Lp(a) with IC50 of 36 nM in in vitro Lp(a) assembly assays. |
