ZYS-1 | ADAR1 inhibitor | Probechem Biochemicals

Chemical Structure : ZYS-1

CAS No.: 2734853-80-4

ZYS-1 (Fludarabine-Cl)

Catalog No.: PC-23996Not For Human Use, Lab Use Only.

ZYS-1 is a potent small-molecule ADAR1 (denosine deaminase acting on RNA 1) inhibitor, suppresses PCa growth and metastasis and potentiated the antitumor immune response.

Packing	Price	Stock
2 mg	$258	In stock
5 mg	$428	In stock
10 mg	$728	In stock
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Biological Activity

ZYS-1 is a potent small-molecule ADAR1 (denosine deaminase acting on RNA 1) inhibitor, suppresses PCa growth and metastasis and potentiated the antitumor immune response.

Physicochemical Properties

M.Wt	303.68
Formula	C10H11ClFN5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,3R,4S,5S)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(chloromethyl)tetrahydrofuran-3,4-diol

References

1. Wang X, et al. Nat Cancer. 2025 Feb 10. doi: 10.1038/s43018-025-00907-4.

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ZYS-1 (Fludarabine-Cl)

Biological Activity

Physicochemical Properties

References

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