Catalog No.: PC-23950Not For Human Use, Lab Use Only.
PKRA7 (PKRA83) is a potent prokineticin receptor 2 (PKR2, PROK2, PK2) antagonist, potently inhibits PK2 receptors with IC50 of 5.0 and 8.2 nM for PKR1 and PKR2, respectively.
PKRA7 (PKRA83) is a potent prokineticin receptor 2 (PKR2, PROK2, PK2) antagonist, potently inhibits PK2 receptors with IC50 of 5.0 and 8.2 nM for PKR1 and PKR2, respectively.
PKRA7 blocks endothelial cell branching, myeloid cell migration, and PK2-induced expression of specific chemokine/chemokine receptors.
PKRA7 decreases subcutaneous and intracranial glioblastoma xenograft tumor growth.
PKRA7 enhances the efficacy of chemotherapeutic drugs to reduce glioblastoma and pancreatic xenograft tumor growth.
