| Cat. No. |
Product Name |
Information |
| PC-73136 |
Naphthyridine-azaquinolone
Slipped-CAG DNA binder
|
Naphthyridine-azaquinolone (NA) is a specific small molecule that specifically binds slipped-CAG DNA intermediates of expansion mutations. |
| PC-73129 |
HG106
SLC7A11 inhibitor
|
HG106 (HG 106) is a potent, selective SLC7A11 inhibitor, selectively kills KRAS-mutant lung adenocarcinoma (LUAD) cells. |
| PC-73111 |
S-181
GCase activator
|
S-181 (S 181) is a specific small-molecule activator (modulator) of β-glucocerebrosidase (GCase) with AC50 of 1.49 uM and a maximum activation of 780%. |
| PC-73101 |
VIT-2763
Ferroportin inhibitor
|
VIT-2763 (Vamifeport, VIT2763) is an oral small molecule inhibitor of ferroportin, inhibits hepcidin binding to ferroportin with IC50 of 9 nM, blocks iron efflux. |
| PC-73090 |
IPA
SNARE inhibitor
|
IPA (Inhibitor of Priming Activity) is a small-molecule compound that binds Sec18 (Kd=3.84 uM) and blocks SNARE activation, inhibits vacuole fusion at the SNARE priming stage with IC50 of 50 uM. |
| PC-73087 |
BRD4780
MUC1-fs mutant inhibitor
|
BRD4780 is a small molecule that releases MUC1-fs from TMED9-enriched compartments and promotes its anterograde trafficking to the lysosome, directly binds to TMED9. |
| PC-73086 |
TMPRSS6 inhibitor Cpd-B
TMPRSS6 inhibitor
|
TMPRSS6 inhibitor Cpd-B (TMPRSS6-IN-Cpd-B) is a highly potent (IC50=7.6 nM), specific small molecule inhibitor of TMPRSS6 (matriptase-2). |
| PC-73085 |
TMPRSS6 inhibitor 8
TMPRSS6 inhibitor
|
TMPRSS6 inhibitor 8 (TMPRSS6-IN-8) is a highly potent (IC50=8.1 nM), peptidomimetic inhibitor of TMPRSS6 (matriptase-2). |
| PC-73083 |
SPI-21
Spt5-Pol II inhibitor
|
SPI-21 (Spt5-Pol II inhibitor 21) is a small-molecule inhibitor of Spt5-Pol II with IC50 of 25.2 uM. |
| PC-73082 |
Endosidin17
VPS35 inhibitor
|
Endosidin17 (ES17) is a small molecule targets retromer component VPS35, binds to VPS35 Impairs interaction with RABG3f, causes dose-dependent stabilization of VPS35 with EC50 of 0.9 uM. |
| PC-73077 |
PCC0208017
pan-MARK inhibitor
|
PCC0208017 is a potent, selective dual small-molecule inhibitor of MARK3 and MARK4 with IC50 of 1.8 and 2.01 nM, respectively. |
| PC-73073 |
Perforin inhibitor 16
Perforin inhibitor
|
Perforin inhibitor 16 (Perforin-IN-16) is a small molecule Perforin inhibitor with IC50 of 1.13 uM in KHYG1 assay. |
