| Cat. No. |
Product Name |
Information |
| PC-72959 |
Etavopivat
PKR activator
|
Etavopivat (FT-4202) is a novel oral activator of PKR that decreases 2,3-DPG levels and hence would increase the HbS O2 affinity to reduce sickling. |
| PC-72948 |
CMP05-7
Endosomolytic compound
|
CMP05-7 (Endosomolytic compound CMP05-7) is a novel endosomolytic small-molecule compound that exhibits higher transfection efficiency/ability to induce endosomal escape of oligonucleotides (ONs) than current compounds such as chloroquine. |
| PC-72947 |
UNC2383
Endosomolytic compound
|
UNC2383 (UNC-2383) is a small molecule that enhances the intracellular delivery and pharmacological effectiveness of antisense oligonucleotides (ONs) and splice switching oligonucleotides (SSOs). |
| PC-72946 |
CMP05
Endosomolytic compound
|
CMP05 (Endosomolytic compound CMP05) is a novel endosomolytic small-molecule compound that exhibits higher transfection efficiency/ability to induce endosomal escape of oligonucleotides (ONs) than current compounds such as chloroquine. |
| PC-72934 |
CELF1-IN-841
CELF1 inhibitor
|
CELF1-IN-841 is a selective CUGBP Elav-like family member 1 (CELF1) inhibitor that disrupted CELF1-RNA binding, targets RRM1/2 of CELF1. |
| PC-72933 |
CELF1-IN-27
CELF1 inhibitor
|
CELF1-IN-27 is a selective CUGBP Elav-like family member 1 (CELF1) inhibitor that disrupted CELF1-RNA binding with IC50 of 23 uM, targets RRM1/2 of CELF1. |
| PC-72921 |
Diethyl-pythiDC
P4HA1 inhibitor
|
Diethyl-pythiDC (diethyl pythiDC) is a selective, small molecule inhibitor of P4HA1, inhibits collagen biosynthesis in breast cancer cells. |
| PC-72918 |
G6PDi-1
G6PD inhibitor
|
G6PDi-1 is a non-steroidal, potent cell active small molecule inhibitor of glucose-6-phosphate dehydrogenase (G6PD) with IC50 of 70 nM (hG6PD). |
| PC-72917 |
IMT1B
POLRMT inhibitor
|
IMT1B (LDC203974) a first-in-class specific inhibitor of mitochondrial transcription that target the human mitochondrial RNA polymerase (POLRMT). |
| PC-72916 |
IMT1
POLRMT inhibitor
|
IMT1 (LDC195943) is a first-in-class specific inhibitor of mitochondrial transcription that target the human mitochondrial RNA polymerase (POLRMT). |
| PC-72915 |
ABA Antagonist AA1
ABA antagonist
|
ABA Antagonist AA1 is a small molecule that inhibits ABA signaling with IC50 of 2.5 uM, targets all ABA receptors. |
| PC-72907 |
YB-0158
Sam68 inhibitor
|
YB-0158 (YB0158) is a β-turn peptidomimetic small molecule altering key hallmarks of human colorectal tumorigenesis, with high predicted affinity for Sam68. |
