| Cat. No. |
Product Name |
Information |
| PC-35386 |
FTBMT
|
FTBMT is a novel selective GPR52 agonist of GPR52, increases intracellular cAMP levels in CHO cells expressing human, mouse, or rat GPR52, with pEC50 of 7.03, 6.85, and 6.87M, respectively. |
| PC-35376 |
SOD1-Derlin-1 inhibitor 56-59
|
SOD1-Derlin-1 inhibitor 56-59 is a cell-permeable, small molecule inhibitor of SOD1-Derlin-1 interaction, target SOD1 DBR and clearly attenuates the interactions of Derlin-1 with 122 types of SOD1mut in the cell-based co-immunoprecipitation assays. |
| PC-35366 |
Lipofermata
Fatty acid transport inhibitor
|
Lipofermata (CB16.2 aka) is a specific fatty acid transport (FATP) inhibitor, blocks human FATP2-mediated fatty acid uptake (IC50=4.84 uM in Caco-2 cells) without impacting other cellular functions. |
| PC-35343 |
5MPN
PFKFB4 inhibitor
|
PFKFB4 inhibitor 5MPN is a first-in-class, selective, competitive, orally available inhibitor of PFKFB4 with Ki of 8.6 uM, does not inhibit PFK-1 or PFKFB3. |
| PC-35335 |
CPSI-1306
MIF inhibitor
|
CPSI-1306 (CPSI1306) is an orally available small-molecule MIF antagonist, protects against UVB-induced squamous cell carcinoma, reduces the severity of animal model of multiple sclerosis. |
| PC-35333 |
EC-359
LIFR inhibitor
|
EC-359 (EC359) is a first-in-class, orally available inhibitor of leukemia inhibitory factor (LIF), blocks LIF-LIFR interaction and binds to LIFR with affinity of 81 nM in SPR assay. |
| PC-35313 |
S-C025
OXE-R inhibitor
|
S-C025 is a highly potent antagonist of oxoeicosanoid receptor (OXE receptor, OXE-R) with IC50 of 0.12 nM. |
| PC-35242 |
Z-590
MIF inhibitor
|
Z-590 is a potent inhibitor of macrophage migration inhibitory factor (MIF) tautomerase activity. |
| PC-35241 |
ISO-92
MIF inhibitor
|
ISO-92 is a potent inhibitor of macrophage migration inhibitory factor (MIF) tautomerase activity with IC50 of 0.55 uM. |
| PC-35233 |
SAN9812
|
SAN9812 (Carnostatine) is a potent, highly selective, competitive inhibitor of Carnosinase 1 (CN1) activity with Ki of 11 nM. |
| PC-35219 |
AZD5904
MPO inhibitor
|
AZD5904 (AZD-5904) is a potent, selective irreversible, orally bioavailable myeloperoxidase (MPO) inhibitor with IC50 of 140 nM, similar potency in mouse and rat. |
| PC-35212 |
4-CPPC
MIF-2 inhibitor
|
4-CPPC is the first reversible and selective inhibitor of pro-inflammatory protein macrophage migration inhibitory factor-2 (MIF-2) with Ki of 33 uM, 13-fold selectivity for human MIF-2 versus human MIF-1. |
