| Cat. No. |
Product Name |
Information |
| PC-35829 |
QM385
|
QM385 (QM-385) is an orally available, potent, specific sepiapterin reductase (SPR) inhibitor (binding IC50=1.49 nM) to limit tetrahydrobiopterin (BH4) production, effectively inhibits the proliferation of human CD4+ T cells. |
| PC-35823 |
iGOT1-01
|
iGOT1-01 is a small molecule inhibitor of aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1 (GOT1)) with IC50 of 11.3 uM. |
| PC-35821 |
AF40431
Sortilin ligand
|
AF40431 (AF-40431) is the first reported small-molecule ligand of the VPS10P family sorting receptor Sortilin with IC50 of 4.4 uM, binds in the neurotensin-binding site of sortilin.. |
| PC-35817 |
Malic Enzyme inhibitor ME1
Malic enzyme ME1 inhibitor
|
Malic Enzyme inhibitor ME1 (ME1) is a small molecule inhibitor of Malic Enzyme (ME1) with IC50 of 0.15 uM. |
| PC-35767 |
APA modulator T5
Alternative polyadenylation modulator
|
APA modulator T5 is a small modulator of alternative polyadenylation (APA), modulates endogenous APA via nonkinase-mediated pathways and promotes distal-to-proximal (DtoP) APA usage in multiple transcripts. |
| PC-35766 |
APA modulator T4
Alternative polyadenylation modulator
|
APA modulator T4 is a small modulator of alternative polyadenylation (APA) with IC50 of 2.1 uM in reporter assays, modulates endogenous APA via nonkinase-mediated pathways and promotes distal-to-proximal (DtoP) APA usage in multiple transcripts. |
| PC-35755 |
PTC299
DHODH inhibitor
|
Emvododstat (PTC-299) is a novel potent inhibitor of dihydroorotate dehydrogenase (DHODH), inhibits hypoxia-induced VEGFA protein production in HeLa cells with IC50 of 1.64 nM. |
| PC-35742 |
HB-MIX1902 Supplement (10X)
|
HB-MIX1902 Supplement (10X) is an optimized serum-free supplement used to promote and maintain the growth, maturity and viability of iPS-derived hepatic and biliary cells. MIX1902 is provided as a 10X liquid and is intended to be used with Hepatocyte Culture Medium for optimal viability and prolonged survival of hepatocytes and cholangiocytes. For detaild user guide, please refer to the PC-3574201 User Guide File Below. |
| PC-35735 |
NEK6 inibitor 8
|
NEK6 inibitor 8 (ZINC05007751) is a novel inhibitor of the NIMA-related kinase NEK6 with IC50 of 3.4 uM, compound 8 is very selective against NEK1 and NEK6, while no signifcant activity was observed against NEK2, NEK7, and NEK9. |
| PC-35723 |
OSMI-4
O-GlcNAc transferase inhibitor
|
OSMI-4 (OGT inhibitor 4b) is a novel potent, selective, cell-active O-linked N-acetylglucosamine transferase (OGT) inhibitor with EC50 of ~3 uM. |
| PC-35722 |
OGT inhibitor 4a
|
OGT inhibitor 4a (OSMI-4 active form) is a novel potent, selective O-linked N-acetylglucosamine transferase (OGT) inhibitor with Kd of 8 nM, the active form of OSMI-4.. |
| PC-35697 |
DKFZ-251
KLK6 inhibitor
|
DKFZ-251 (DKFZ251) is a selective inhibitor of Kallikrein-related peptidase 6 (KLK6) with IC50 of 0.13 uM, demonstrates good selectivity for KLK6 compared to other KLKs. |
