| Cat. No. |
Product Name |
Information |
| PC-49704 |
NUP-17d-52A
Plek2 inhibitor
|
NUP-17d-52A (Plek2 inhibitor) is a specific small molecule inhibitor of Pleckstrin-2 (Plek2), binds to Plek2-DEP domain with high affinity (Kd=160 nM). |
| PC-49703 |
Plek2 inhibitor NUP-17d
Plek2 inhibitor
|
Plek2 inhibitor NUP-17d is a specific small molecule inhibitor of Pleckstrin-2 (Plek2), binds to Plek2 and Plek2-DEP with high affinity (ITC KD=109 and 350 nM, respectively). |
| PC-49693 |
Xist inhibitor X1
Xist inhibitor
|
Xist inhibitor X1 is a selective small molecule inhibitor of the non-coding RNA prototype Xist function, binds specifically to the RepA motif of Xist (Kd=0.4 uM) in vitro and in vivo. |
| PC-49692 |
VPS41 inhibitor DMBP
VPS41 inhibitor
|
DMBP is a natural small molecule with preferable anticancer activity, inhibits vacuolar protein sorting-associated protein 41 homolog (VPS41) function, a subunit of the HOPS complex. |
| PC-49685 |
MPO inhibitor IN-4
MPO inhibitor
|
MPO inhibitor IN-4 is a highly potent, selective, irreversible and orally bioavailable myeloperoxidase (MPO) inhibitor. |
| PC-49677 |
PDS-0330
Claudin-1 inhibitor
|
PDS-0330 (PDS0330) is a first-generation, specific small molecule claudin-1 inhibitor with Kd of 22.9 uM in MST binding assays, impairs the interaction between claudin1 and pSrc/Src and alters survival signaling pathways. |
| PC-49675 |
DS07551382
PTDSS1 inhibitor
|
DS07551382 (DS 07551382) is potent, selective and orally active PTDSS1 (phosphatidylserine synthetase 1), suppresses phosphatidylserine (PS) production activity of PTDSS1 (IC50=100 nM) in cell-free assays, but not that of PTDSS2. |
| PC-49648 |
FK3453
TSLP inhibitor
|
FK3453 (FK 3453) is a novel inhibitor of thymic stromal lymphopoietin (TSLP) production, reduces both TSLP protein levels and mRNA levels both in vitro and in vivo. |
| PC-49645 |
TH8535
OGG1 inhibitor
|
TH8535 (TH-8535) is a potent, selective inhibitor of 8-oxo Guanine DNA Glycosylase 1 (OGG1) with IC50 of 0.2 uM. |
| PC-49633 |
BI-3231
HSD17B13 inhibitor
|
BI-3231 (BI 3231) is a potent, selective HSD17B13 (hydroxysteroid 17β-dehydrogenase 13) inhibitor with enzyme IC50 of 1 and 14 nM for human and mouse HSD17B13, respectively. |
| PC-49632 |
BI-0955
HSD17B13 inhibitor
|
BI-0955 is an inactive HSD17B13 control compound for BI-3231. |
| PC-49630 |
Levetiracetam
SV2A ligand
|
Levetiracetam (UCB L059) an antiepileptic drug with a unique activity profile in animal models of seizure and epilepsy, binds to (pKi=5.2) and modulates synaptic vesicle protein SV2A. |
