| Cat. No. |
Product Name |
Information |
| PC-28384 |
DANA
Neuraminidase inhibitor
|
DANA (Neu5Ac2en, 2,3-dehydro-2-deoxy-N-acetylneuraminic acid) is a potent Neuraminidas isoenyzmes (Sialidases, NEU) inhibitor with IC50 of 49, 43, 7.7, and 8.3 uM for NEU1, NEU2, NEU3, and NEU4, respectively, shows anti-influenza virus activity. |
| PC-28362 |
JP4-039
Antioxidant
|
GS-nitroxide (JP4-039) is a mitochondrion-targeted antioxidant nitroxide and mitochondria-targeted reactive species (ROS) scavenger and electron scavenger. |
| PC-28361 |
Gramicidin S
Antibiotic
|
Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic that selectively targets bacterial cell membranes and has anticancer activity, selectively accumulates within microbial cell membranes. |
| PC-28352 |
DMNB-7d
GPR52 agonist
|
DMNB-7d is a photoactivatable GPR52 agonist, shows markedly reduced basal activity in the dark and underwent photoactivation under 405 nM irradiation in cells. |
| PC-28350 |
δ-secretase inhibitor 11a
AEP inhibitor
|
δ-secretase inhibitor 11a (AEP inhibitor CP#11A) is a potent, selective δ-secretase (Asparagine endopeptidase, AEP, Legumain) inhibitor with IC50 of 10 nM, and binding affinity Kd of 5.5 nM. |
| PC-28333 |
Hopantenate calcium
PANK inhibitor
|
Hopantenate Calcium (HoPan) is a pantothenate analogue hopantenate (HoPan) widely used as a modulator of coenzyme A (CoA) levels, inhibits pantothenate kinase (PanK), the first enzyme of CoA biosynthesis, also inhibits inhibits the next enzyme phosphopantothenoylcysteine synthetase (PPCS) in CoA pathway. |
| PC-28329 |
BBP-671
PANK3 activator
|
Claziprotamide (BBP-671) is a potent, brain penetrant small molecule activator of Pantothenate kinase (PanK) with Kd of 97 pM and IC50 of 1.59 nM for PanK3, binds to and activates all PANK isoforms. |
| PC-28328 |
PZ-3022
PANK3 activator
|
PZ-3022 is an allosteric, orally bioavailable Pantothenate kinase (PanK) activator with EC50 of 5.3 nM against PanK3, shows a lower affinity for PanK isoforms PANK1β and PANK2m with EC50 of 789 nM and 15 nM respectively. |
| PC-28327 |
VTAC-2
PANK3 activator
|
VTAC-2 is a specific, direct small molecule activator of human PANK3 (Pantothenate kinase 3) with EC50 of 76.5 nM, shows no effect on the catalytic activity of hPANK1 or hPANK2. |
| PC-28234 |
Cytochalasin D
Actin polymerization inhibitor
|
Cytochalasin D (Zygosporin A, CytoD) is a specific inhibitor of actin polymerization, inhibits the G-actin-cofilin interaction by binding to G-actin, also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. |
| PC-28217 |
AIGM-2024-4
YB-1 modulator
|
AIGM-2024-4 is a small molecule modulator of Y-Box Binding Protein-1 (YB-1, YBX-1) with MST KD of 1.24 uM, significantly reduces tumor growth in DMBA- induced rat mammary tumor model, accompanied by altered expression of YB-1 and tumor progression associated proteins, including HER2, EGFR, ERα, and Ki-67, together with increased E-cadherin expression. |
| PC-28178 |
Naringenin
DENV RdRp inhibitor, MARK4 inhibitor
|
Naringenin is a flavanone in Citrus reticulata Blanco within anti-inflammatory and antioxidant activities, monocarboxylate transporter 1 (MCT1) in Caco-2 cells with Ki of 15-20 uM, also inhibits DENV RNA-dependent RNA polymerase (RdRp), is also a potent inhibitor of MARK4 with IC50 of 4.11 uM. |
