Chemical Structure : KK023-N1
CAS No.:
KK023-N1
Catalog No.: PC-27201Not For Human Use, Lab Use Only.
KK023-N1 is a potent, specific Striga germination inhibitor, blocks the hydrolysis activity of S. hermonthica HYPO-SENSITIVE TO LIGHT 7 (ShHTL7) with IC50 of 1.78 uM, does not affect rice (Oryza sativa) SL receptor DWARF14 (OsD14).
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Purity & Documentation Purity:
>98% (HPLC)
Biological Activity
KK023-N1 is a potent, specific Striga germination inhibitor, blocks the hydrolysis activity of S. hermonthica HYPO-SENSITIVE TO LIGHT 7 (ShHTL7) with IC50 of 1.78 uM, does not affect rice (Oryza sativa) SL receptor DWARF14 (OsD14).
KK023-N1 does not impact rice seeds growth or tillering.
KK023-N1 inhibits Striga seed germination.
KK023-N1 blocks the ShHTL7 binding pocket and thus prevents the SL-dependent interaction with ShMAX2.
KK023-N1 reduces Striga emergence in infested rice under greenhouse conditions.
Striga hermonthica, a root parasitic weed that infests a diverse range of crops, germinates through the perception of host-derived strigolactones (SLs) with receptor protein ShHTL.
Physicochemical Properties
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M.Wt
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362.43
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Formula
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C21H22N4O2
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20°C 12 Months; 4°C 6 Months
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- In Solvent
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-80°C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO
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Chemical Name/SMILES
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(4-(3-(4-methoxyphenyl)propyl)indolin-1-yl)(1H-1,2,3-triazol-1-yl)methanone
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References
1. Randa A Zarban, et al. Plant Physiol. 2022 Feb 4;188(2):1369-1384.
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