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SB-583355

Chemical Structure : SB-583355

CAS No.: 3040121-49-8

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SB-583355 (SB583355)

Catalog No.: PC-27049Not For Human Use, Lab Use Only.

SB-583355 is a potent, peptidomimetic inhibitor of GPR132 (G2A), inhibits agonist-induced hGPR132aPL association with β-arrestin with pIC50 of 7.0.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SB-583355 is a potent, peptidomimetic inhibitor of GPR132 (G2A), inhibits agonist-induced hGPR132aPL association with β-arrestin with pIC50 of 7.0.

Physicochemical Properties

M.Wt 472.59
Formula C29H32N2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-N-(1-(cyclohexylamino)-1-oxo-3-phenylpropan-2-yl)-6-hydroxy-4'-methoxy-[1,1'-biphenyl]-3-carboxamide

References

1. James R Foster, et al. Pharmacol Res Perspect. 2019 Nov 21;7(6):e00542.

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