| Cat. No. |
Product Name |
Information |
| PC-61428 |
Ibiglustat
Glucosylceramide synthase inhibitor
|
Ibiglustat (Venglustat, Genz-682452) is an orally active, selective and potent Glucosylceramide synthase (GCS) inhibitor with central nervous system (CNS) access. |
| PC-61427 |
EXEL-0346
Glucosylceramide synthase inhibitor
|
EXEL-0346 (EXEL0346) is a novel potent, orally active Glucosylceramide synthase (GCS) inhibitor with IC50 of 2 nM. |
| PC-61426 |
CCG-203586
Glucosylceramide synthase inhibitor
|
CCG-203586 is a potent, CNS-active Glucosylceramide synthase (GCS) inhibitor with IC50 of 27 nM. |
| PC-61425 |
PDMP hydrochloride
Glucosylceramide synthase inhibitor
|
PDMP hydrochloride is a ceramide analog that inhibits glucosylceramide synthase (GCS), reduces the synthesis of sphingosine and its derivatives, increases cellular ceramide, and induces cell cycle arrest. |
| PC-61424 |
Fumonisin B1
Ceramide synthase inhibitor
|
Fumonisin B1 is a mycotoxin produced from F. moniliforme, and an inhibitor of ceramide synthase (sphingosine N-acyltransferase/CerS). |
| PC-61423 |
Myriocin
Serine palmitoyltransferase inhibitor
|
Myriocin (ISP-1) is an amino fatty acid antibiotic that is 10- to 100-fold more potent than cyclosporin A as an immunosuppressive agent of the immune response in vitro and in vivo. |
| PC-61401 |
Tepilamide fumarate
|
Tepilamide fumarate (XP 23829, PPC-06) s a small-molecule, fumaric acid ester (FAE) compound that is a prodrug of methyl hydrogen fumarate (also known as monomethyl fumarate), for the treatment of relapsing-remitting multiple sclerosis and plaque psoriasis. |
| PC-61399 |
Setafrastat
|
Setafrastat is a small molecule hair growth stimulator. |
| PC-61393 |
Parimifasor
ATPase modulator
|
Parimifasor (LYC-30937-EC, LYC30937) is an orally bioavailable, enteric-coated ATPase modulator as a gut-directed therapy for the treatment of inflammatory bowel disease (IBD). |
| PC-61376 |
Epeleuton
|
Epeleuton is an orally administered, second-generation ω-3 fatty acid derivative of C20:5 n-3 EPA, protects against cellular stress associated with SCD and supports early initiation of the resolution phase of inflammation. |
| PC-61375 |
Enexasogaol
PPARγ agonist
|
Enexasogaol (6-Shogaol) is a pungent agent isolated from Zingiber officinale Roscoe, has been known to have anti-tumor and anti-inflammatory effects. |
| PC-61361 |
Spindlactone B
TACC3 inhibitor
|
Spindlactone B (SPL-B) is a novel small molecule inhibitor of transforming acidic coiled-coil-containing protein 3 (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells. |
