Chemical Structure : PIT-1
CAS No.:
53501-41-0
PIT-1
(PIP3 antagonist)
Catalog No. : PC-62042Not For Human Use, Lab Use Only.
PIT-1 is a specific PIP3 antagonist that disrupts PIP3/Akt PH domain binding with IC50 of 30 uM, Kd of 43.2 uM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6204201
Biological Activity
PIT-1 is a specific PIP3 antagonist that disrupts PIP3/Akt PH domain binding with IC50 of 30 uM, Kd of 43.2 uM.
Physicochemical Properties
M.Wt
351.76
Formula
C14H10ClN3O4S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
N-[[(3-chloro-2-hydroxy-5-nitrophenyl)amino]thioxomethyl]-benzamide
References
1. Miao B, et al. Proc Natl Acad Sci U S A.
2. Manna P, et al. Cell Physiol Biochem.
3. Miao B, et al. Oncogene.
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