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Chemical Structure : MitoBloCK 1
Catalog No.: PC-62047Not For Human Use, Lab Use Only.
MitoBloCK 1 is a small molecule inhibitor that blocks the import of substrates that use the TIM22 import pathway, but not TIM23 or the Mia40/Erv1 translocation pathways.
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MitoBloCK 1 is a small molecule inhibitor that blocks the import of substrates that use the TIM22 import pathway, but not TIM23 or the Mia40/Erv1 translocation pathways.
MitoBloCK 1 also inhibits growth of mammalian cells and import of the ADP/ATP carrier, but not TIM23 substrates.
MitoBloCK 1 is an useful chemical tool for investigation mammalian mitochondrial import and dysfunction linked to inherited human disease.
| M.Wt | 368.249 | |
| Formula | C14H14BrN3O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hasson SA, et al. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9578-83.
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