| Cat. No. |
Product Name |
Information |
| PC-27605 |
AM404
Anandamide transport inhibitor
|
AM404 is a seletive inhibitor of anandamide transport with IC50 of 2.2 uM, does not activate cannabinoid receptors or inhibit anandamide hydrolysis. |
| PC-27602 |
Pyridoxal Isonicotinoyl Hydrazone
Ferrochelatase inhibitor, Iron chelator
|
Pyridoxal isonicotinoyl hydrazone (PIH) is an orally active and lipophilic iron-specific chelator that acts as a non-competitive inhibitor of ferrochelatase (FECH) by binding iron ions. |
| PC-27597 |
Afegostat tartrate
Glycosidase inhibitor
|
Afegostat tartrate (Isofagomine D-Tartrate, AT2101) is a broad spectrum inhibitor of glycosidases, inhibits beta-glucosidase, glucoamylase, isomaltase, and alpha-glucosidase, specifically and reversibly binds lysosomal hydrolase acid β-glucosidase (GCase) in the ER with high affinity. |
| PC-27582 |
dPTBD
Cuproptosis inducer
|
dPTBD is a copper ionophore and cuproptosis inducer, promotes intracellular copper accumulation particularly in the mitochondria, leading to metabolic disruption and cuproptotic cell death, exhibits significant antitumor efficacy in KRAS-driven cancers both in vitro and in vivo. |
| PC-27560 |
EZ-482
ApoE ligand, ApoE inhibitor
|
EZ-482 is a small molecule ligand of Apolipoprotein E (ApoE), binds to the C-terminal domains of both ApoE3 and ApoE4 with KD of approximately 8 μM, blocks heparin binding to the N-terminal domain. |
| PC-27550 |
Rhoifolin
CAS 17306-46-6
|
Rhoifolin is a natural flavonoid with anti-inflammatory and antiparasitic potential, is a a direct potassium channel modulatory factor 1 (KCMF1) binder that stabilizes AMPKα and ameliorates MASLD, also inhibits the specific binding site of ALDH2-PKCδ, significantly increases chemosensitivity. |
| PC-27549 |
Helveticoside
CAS 630-64-8
|
Helveticoside is a natural compound extract of Descurainia sophia, induces reciprocal gene regulation in A549 human lung cancer cells, shows p53-dependent anti-cancer activity of aginst colorectal cancer cells SW480 and HCT116. |
| PC-27535 |
HA-CD44 inhibitor JE22
CD44 inhibitor
|
HA-CD44 inhibitor JE22 is a small molecule Hyaluronic acid (HA)-CD44 interaction inhibitor, effectively blocks HA-CD44 binding, shows antiproliferative activity with EC50 of 8 uM against the CD44+ breast cancer tumor line MDA-MB-231. |
| PC-27534 |
HA-CD44 inhibitor 4
CD44 inhibitor
|
HA-CD44 inhibitor 4 is a potential Hyaluronic acid (HA)-CD44 interaction inhibitor, effectively blocks HA-CD44 binding, shows antiproliferative activity against MDA-MB-231 cells with EC50 of 3.58 uM. |
| PC-27533 |
HA-CD44 inhibitor 3
CD44 inhibitor
|
HA-CD44 inhibitor 3 is a potential Hyaluronic acid (HA)-CD44 interaction inhibitor, effectively blocks HA-CD44 binding, shows antiproliferative activity against MDA-MB-231 cells with EC50 of 4.24 uM. |
| PC-27532 |
HA-CD44 inhibitor 2
CD44 inhibitor
|
HA-CD44 inhibitor 2 is a potential Hyaluronic acid (HA)-CD44 interaction inhibitor, effectively blocks HA-CD44 binding, shows antiproliferative activity against MDA-MB-231 cells with EC50 of 0.59 uM. |
| PC-27531 |
HA-CD44 inhibitor 1
CD44 inhibitor
|
HA-CD44 inhibitor 1 is a potential Hyaluronic acid (HA)-CD44 interaction inhibitor, effectively blocks HA-CD44 binding, shows antiproliferative activity against MDA-MB-231 cells with EC50 of 1.77 uM. |
