| Cat. No. |
Product Name |
Information |
| PC-22298 |
CtBP1/BARS inhibitor Comp.11
CtBP1/BARS inhibitor
|
CtBP1/BARS inhibitor Comp.11 is a potent, selective inhibitor targeting the C-terminal-binding protein 1/brefeldin A ADP-ribosylation substrate (CtBP1/BARS), directly binds and inhibits the CtBP1/BARS protein-partners interaction with Kd of 0.66 uM. |
| PC-22285 |
MS-L6
OXPHOS inhibitor
|
MS-L6 is a novel small molecule OXPHOS inhibitor, exerts dual mitochondrial effects: mitochondrial electron transport chain complexe ETC-I inhibition and uncoupling of OXPHOS. |
| PC-22255 |
SC26196
D6D inhibitor
|
SC26196 (SC-26196) is a potent, selective delta6 desaturase (Δ6 desaturase, D6D, FADS2) inhibitor with IC50 of 0.2 uM in rat liver microsomal assay. |
| PC-22249 |
PRDX1 inhibitor 15
PRDX1 inhibitor
|
PRDX1 inhibitor 15 is a potent, selective and covalent peroxiredoxin (PRDX1) inhibitor with IC50 of 0.35 uM, covalently binds to Cys-173 of PRDX1 with KD of 0.37 uM, shows antiproliferative potency against colon cancer cells. |
| PC-22248 |
PRDX1 inhibitor H7
PRDX1 inhibitor
|
PRDX1 inhibitor H7 is a specific small molecule inhibitor of antioxidant enzyme peroxiredoxin I (Prdx I) with IC50 of 7.85 uM, induces leukemia-cell differentiation in vitro and in vivo. |
| PC-22240 |
FCW393
Sialyltransferase inhibitor
|
FCW393 is a potent, selective sialyltransferase inhibitor with IC50 of 7.8 uM and 9.48 uM for ST6GAL1 and ST3GAL3, does not inhibit ST3GAL1 and ST8SIA4 (IC50>100 uM), suppresses cancer metastasis. |
| PC-22222 |
Leflunomide
DHODH inhibitor
|
Leflunomide is a potent dihydroorotate dehydrogenase (DHODH) and pyrimidine synthesis inhibitor with IC50 of 208.5 nM in cell-free human DHODH enzyme inhibition assays. |
| PC-22221 |
HOSU-53 sodium
DHODH inhibitor
|
HOSU-53 sodium is selective and potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 0.95 nM in cell-free human DHODH enzyme inhibition assays. |
| PC-22220 |
HOSU-53
DHODH inhibitor
|
HOSU-53 is selective and potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 0.95 nM in cell-free human DHODH enzyme inhibition assays. |
| PC-22199 |
BAY R3401
Glycogen phosphorylase inhibitor
|
BAY R3401 is a potent, competive glycogen phosphorylase inhibitor, inhibits muscle glycogen phosphorylase a and b. |
| PC-22198 |
Bay W1807
Glycogen phosphorylase inhibitor
|
BAY W1807 is a potent, competive glycogen phosphorylase inhibitor with Ki of 1.6 nM for rabbit muscle glycogen phosphorylase b (GPb), inhibits muscle glycogen phosphorylase a and b. |
| PC-22184 |
Tacrolimus
FKBP ligand
|
Tacrolimus (FK506) is a macrocyclic lactone that binds to FK506 binding protein (FKBP) to form a complex, inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription, shows immunosuppressive properties. |
