Cat. No. |
Product Name |
Information |
PC-20929 |
DLin-MC4-DMA
|
D-Lin-MC4-DMA is an ionizable lipid used for development of lipidoid nanoparticles for siRNA, mRNA, and vaccine delivery. |
PC-20927 |
Cantrixil
CAS 2135511-22-5
|
Cantrixil (TRX-E-002-1) is a potent inducer of CD44+/MyD88+ ovarian cancer stem cell (OCSC) death with IC50 of 47 nM. |
PC-20909 |
GPR56 agonist 36
GPR56 agonist
|
GPR56 agonist 36 is a potent selective agonist of adhesion GPCR ADGRG1/GPR56 with EC50 of 2.95 uM. |
PC-20902 |
Luvadaxistat
DAAO inhibitor
|
TAK-831 (Luvadaxistat, NBI-1065844) is a highly potent, selective D-amino acid oxidase (DAAO) inhibitor with IC50 of 14 nM against human recombinant DAAO enzyme. |
PC-20890 |
Lalistat-1
LAL inhibitor
|
Lalistat 1 is a potent and selective lysosomal acid lipase (LAL) inhibitor with IC50 of 68 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase. |
PC-20889 |
Lalistat-2
LAL inhibitor
|
Lalistat-2 (L-stat) is a specific inhibitor of lysosomal acid lipase (LAL) with IC50 of 152 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase. |
PC-20883 |
NCI-41356
CRYAB inhibitor
|
NCI-41356 is a small molecular inhibitor of αB-crystallin (CRYAB, HSPB5), significantly reducesthe interaction between CRYAB and VEGF165. |
PC-20871 |
NVP-231
CerK inhibitor
|
NVP-231 (NVP231) is a potent, specific, and reversible ceramide kinase (CerK) inhibitor with IC50 of 12 nM. |
PC-20868 |
Imanixil
LDLR inducer
|
Imanixil (HOE402) is a small molecule inducer of the LDL receptor (LDLR), HOE402 is a potent cholesterol-lowering compound, inhibits VLDL production. |
PC-20866 |
ARUK200282
PI5P4Kα inhibitor
|
ARUK200282 is a potent, isoform-selective PI5P4Kα inhibitor with pIC50 of 8.0, selective over PI5P4Kβ and PI5P4Kγ. |
PC-20859 |
LI-2242
IP6K inhibitor
|
LI-2242 is a potent pan-IP6K inhibitor with IC50 of with IC50 of 31, 42 and 8.1 nM for IP6K1, IP6K2 and IP6K3, respectively. |
PC-20846 |
CC-410
NNMT inhibitor
|
CC-410 (CC410) is a potent, specific inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 of 1.6 uM (human NNMT). |