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Cat. No. Product Name Information
PC-22249

PRDX1 inhibitor 15

PRDX1 inhibitor

PRDX1 inhibitor 15 is a potent, selective and covalent peroxiredoxin (PRDX1) inhibitor with IC50 of 0.35 uM, covalently binds to Cys-173 of PRDX1 with KD of 0.37 uM, shows antiproliferative potency against colon cancer cells.
PC-22248

PRDX1 inhibitor H7

PRDX1 inhibitor

PRDX1 inhibitor H7 is a specific small molecule inhibitor of antioxidant enzyme peroxiredoxin I (Prdx I) with IC50 of 7.85 uM, induces leukemia-cell differentiation in vitro and in vivo.
PC-22240

FCW393

Sialyltransferase inhibitor

FCW393 is a potent, selective sialyltransferase inhibitor with IC50 of 7.8 uM and 9.48 uM for ST6GAL1 and ST3GAL3, does not inhibit ST3GAL1 and ST8SIA4 (IC50>100 uM), suppresses cancer metastasis.
PC-22222

Leflunomide

DHODH inhibitor

Leflunomide is a potent dihydroorotate dehydrogenase (DHODH) and pyrimidine synthesis inhibitor with IC50 of 208.5 nM in cell-free human DHODH enzyme inhibition assays.
PC-22221

HOSU-53 sodium

DHODH inhibitor

HOSU-53 sodium is selective and potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 0.95 nM in cell-free human DHODH enzyme inhibition assays.
PC-22220

HOSU-53

DHODH inhibitor

HOSU-53 is selective and potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 0.95 nM in cell-free human DHODH enzyme inhibition assays.
PC-22199

BAY R3401

Glycogen phosphorylase inhibitor

BAY R3401 is a potent, competive glycogen phosphorylase inhibitor, inhibits muscle glycogen phosphorylase a and b.
PC-22198

Bay W1807

Glycogen phosphorylase inhibitor

BAY W1807 is a potent, competive glycogen phosphorylase inhibitor with Ki of 1.6 nM for rabbit muscle glycogen phosphorylase b (GPb), inhibits muscle glycogen phosphorylase a and b.
PC-22184

Tacrolimus

FKBP ligand

Tacrolimus (FK506) is a macrocyclic lactone that binds to FK506 binding protein (FKBP) to form a complex, inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription, shows immunosuppressive properties.
PC-22182

RSMI-29

Ricin inhibitor

RSMI-29 is a small molecule inhibitor of ricin toxin, specifically targeting ricin toxin A chain (RTA) with binding KD of 0.9 uM, inhibits cytotoxicity of RTA/ricin.
PC-22178

Trolox

Antioxidant agent

Trolox is a water-soluble vitamin E analogue and antioxidant agent, scavenges peroxyl radicals better than vitamin E in sodium dodecyl sulfate micelles and in liposomes.
PC-22173

Compound 797780-71-3

DJ-1/PARK7 inhibitor

Compound 797780-71-3 is a small molevcule, covalent inhibitor of DJ-1 (PARK7), effectively inhibits the proliferation of ACHN cells with IC50 of 12.18 uM, inhibits the Wnt signaling pathway.

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