| Cat. No. |
Product Name |
Information |
| PC-23722 |
QP5020
QPCTL inhibitor
|
QP5020 is a potent inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with IC50 of 15 nM. |
| PC-23698 |
SEPT9 inhibitor 8b
SEPT9 inhibitor
|
SEPT9 inhibitor 8b is a small molecule inhibitor of Septin 9 (SEPT9) with IC50 of 95 uM in fluorescence polarization (FP) assays, and binding KD of 22 uM, disrupts the structure of SEPT9, microtubules, and actin filaments. |
| PC-23697 |
Neocarzilin A
VAT1 inhibitor
|
Neocarzilin A (NCA) is a potent inhibitor of cancer cell migration, irreversibly binds to and inhibits the synaptic vesicle membrane protein VAT-1. |
| PC-23649 |
Genipin
UCP2 inhibitor
|
Genipin is a specific small molecule inhibitor of uncoupling protein 2 (UCP2), inhibits UCP2-mediated mitochondrial proton leak. |
| PC-23604 |
CCG257081
MRTF/SRF inhibitor
|
CCG-257081 is a small molecule MRTF/SRF pathway inhibitor, shows direct binding to pirin with ITC KD value of 8.6 uM, inhibits melanoma metastasis and bleomycin-induced fibrosis. |
| PC-23586 |
NB-598
Squalene epoxidase inhibitor
|
NB-598 (NB598) is a potent competitive inhibitor of squalene epoxidase (SQLE, SE, squalene monooxygenase) with IC50 of 4.4 nM (rat SE), inhibits microsomal squalene epoxidase from dog liver and Hep G2 cells with IC50 of 2.0 and 0.75 nM, respectively. |
| PC-23580 |
Licochalcone C
α-glycosidase inhibitor
|
Licochalcone C is a selective inhibitor of α-glycosidase with IC50 of <100 nM, does not inhibit PTP1B, induces apoptosis via Bcl-2 family proteins in T24 cells. |
| PC-23578 |
Licochalcone A
UGT inhibitor
|
Licochalcone A is a broad-spectrum inhibitor of UDP-glucuronosyltransferase (UGT) with IC50/Ki values of <5 uM for UGT1A1、1A3、1A4、1A6、1A7、1A9 and 2B7, shows anti-cancer effects, |
| PC-23556 |
Purpurin
GDH1 inhibitor
|
Purpurin is a potent, specific inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1) with Ki of 1.9 uM, inhibits cancer cell proliferation and tumor growth. |
| PC-23544 |
LH1513
CaOx crystallization inhibitor
|
LH1513 (L-Lysine Dioxalate) is potent inhibitor of calcium oxalate (CaOx) crystallization with EC50 of 21.7 uM. |
| PC-23540 |
FPD5
Esterase D inhibitor
|
FPD5 is a small molecule activator of esterase D (ESD) with KD value of 0.8 nM, directly binds to ESD at Lys180 rather than its ubiquitination site Lys213. |
| PC-23538 |
WYFA15
SMS1 inhibitor
|
WYFA15 is a small molecule inhibitor of sphingomyelin synthase 1 (SMS1), inhibits severe fever with thrombocytopenia syndrome virus (SFTSV) infection and reduces SARS-CoV-2 replication and pathogenesis. |
