| Cat. No. |
Product Name |
Information |
| PC-62059 |
FSC 231
|
FSC 231 (FSC231) is the first, cell-permeable small-molecule inhibitor of PICK1 PDZ domain with Kd of 10.1 uM. |
| PC-62048 |
MitoBloCK 6
|
MitoBloCK 6 is a small molecule mitochondrial protein import blocker that inhibits Erv1 oxidase activity. |
| PC-62047 |
MitoBloCK 1
TIM22 inhibitor
|
MitoBloCK 1 is a small molecule inhibitor that blocks the import of substrates that use the TIM22 import pathway, but not TIM23 or the Mia40/Erv1 translocation pathways. |
| PC-62043 |
DM-PIT-1
PIP3 antagonist
|
DM-PIT-1 is a specific PIP3 antagonist that disrupts PIP3/Akt PH domain, PIP3/PDK1 PH domain, and PIP3/GRP1 PH domain with IC50 of 27.1 uM, 80.5 uM, and 35.5 uM, respectively. |
| PC-62042 |
PIT-1
PIP3 antagonist
|
PIT-1 is a specific PIP3 antagonist that disrupts PIP3/Akt PH domain binding with IC50 of 30 uM, Kd of 43.2 uM. |
| PC-62028 |
BRD8899
STK33 inhibitor
|
BRD 8899 is a potent and selective inhibitor of the serine/threonine kinase STK33 with IC50 of 0.11 nM (25 uM ATP). |
| PC-61994 |
TK216
EWS-FLI1 inhibitor
|
TK216 is a first in class, small molecule that directly binds EWS-FLI1 inhibiting the biological activity of ETS-family transcription factor oncoproteins and is currently under clinical investigation against Ewing sarcoma.. |
| PC-61855 |
Elamipretide
|
Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell type. |
| PC-61825 |
NS-3-008
|
NS-3-008 is a novel small-molecule transcriptional inhibitor of G0s2 (G0/G1 switch 2) with IC50 of 2.25 uM. |
| PC-61813 |
FEN1-IN-C20
FEN1 inhibitor
|
FEN1-IN-C20 is an N‐hydroxyl urea derivative that specifically inhibits flap endonuclease 1 (FEN1) activity with IC50 of 3 nM. |
| PC-61796 |
Trofinetide
|
Trofinetide (NNZ 2566) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration. |
| PC-61784 |
NSC 15765
DNA2 nuclease inhibitor
|
NSC 15765 (Compound C5, DNA2 inhibitor C5) is an effective, selective and competitive inhibitor of DNA2 nuclease with IC50 of 20 uM. |
