You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets

Request The Product List ofOther Targets Other Targets

Cat. No. Product Name Information
PC-72124

AGF347

SHMT2 inhibitor

AGF347 (AGF-347) is a small molecule inhibitor targeting mitochondrial C1 metabolism at SHMT2 (in vitro Ki=2.19 uM), also directly targers the purine biosynthetic enzymes GARFTase (Ki=3.13 uM) and AICARFTase (Ki=3.72 uM), and SHMT1 (Ki=2.91 uM).
PC-72110

MK-8719

O-GlcNAcase inhibitor

MK-8719 (MK8719) is a a highly potent, selective, CNS-penetrable inhibitor of O-GlcNAcase (OGA) with Ki of 7.9 nM (hOGA).
PC-72103

AM9053

NAAA inhibitor

AM9053 (AM 9053) is a potent, selective inhibitor of N-Acylethanolamine acid amidase (NAAA) with IC50 of 30 nM, with limited effect on FAAH activity (IC50>100 uM).
PC-72102

ARN19689

NAAA inhibitor

ARN19702 (ARN-19702) is potent, selective, non-covalent inhibitor of N-Acylethanolamine acid amidase (NAAA) with IC50 of 42 nM (h-NAAA).
PC-72101

ARN19702

NAAA inhibitor

ARN19702 (ARN-19702) is potent, selective, orally active, reversible inhibitor of N-Acylethanolamine acid amidase (NAAA) with IC50 of 230 nM.
PC-72080

GMFBI.1

GMF-β inhibitor

GMFBI.1 is a small molecule that specifically block Ser83 phosphorylation site on Glia maturation factor-β (GMF-β), directly binds to hGMF-β protein with Kd of 19.9 uM.
PC-72079

INH-12

HSD17B12 inhibitor

INH-12 is a selective small-molecule HSD17B12 inhibitor with 70% inhibition of HSD17B12 activity to transform estrone (E1) into estradiol (E2) at 1 uM, reduces the replication of Flaviviridae viruses (HCV, DENV and ZIKV).
PC-72078

NCGC00507974

Mir155 inhibitor

NCGC00507974 is a small molecule inhibitor of Mir155 reporter, dose-dependently inhibits Mir155 reporter expression with EC50 of 1.2 uM.
PC-72077

NCGC00108248

Mir155 inhibitor

NCGC00108248 is small molecule inhibitor of Mir155 reporter, dose-dependently inhibits Mir155 reporter expression with EC50 of 2.2 uM.
PC-72076

ClpXP inhibitor 334

ClpXP inhibitor

ClpXP inhibitor 334 is a small molecule inhibitor of the mitochondrial ClpXP protease with anti-cancer activity.
PC-72071

hNPR1 inhibitor JS-11

NPR1 inhibitor

hNPR1 inhibitor JS-11 is a selective small-molecule inhibitor of NPPB receptor NPR1 (natriuretic peptide receptor 1), does not inhibit adenylate cyclases (ACs) family of enzymes.
PC-72067

ALC-0159

PEGylated lipid

ALC-0159 is a PEGylated lipid which has been used to form lipid nanoparticles for delivery of RNA. ALC-0159 is one of the components in the BNT162b2 vaccine against SARS-CoV-2 in addition to ALC-0315, DSPC, and cholesterol.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com