| Cat. No. |
Product Name |
Information |
| PC-72463 |
BAY-091
PIP4K2A inhibitor
|
BAY-091 (BAY091) is a potent and highly selective inhibitor of PIP4K2A with IC50 of 16 nM in the high ATP (2 mM) HTRF assay. |
| PC-72461 |
MLS000544460
EYA2 inhibitor
|
MLS000544460 (EYA2i) is a specific, allosteric inhibitor of Eya2 phosphatase with IC50 of 4.1 uM, KD of 2.0 uM, does not bind Eya3 ED, Eya1 and Eya4 ED. |
| PC-72458 |
JumOCA peptide
OCA-B peptide inhibitor
|
JumOCA peptide (VKELLRRKRGH) is a peptide corresponding to the transcriptional coregulator OCA-B N terminus, membrane-penetrating OCA-B peptide inhibitor. |
| PC-72452 |
NCGC00249987
EYA2 inhibitor
|
NCGC00249987 (Compound 9987) is a small-molecule allosteric inhibitor that specifically inhibits the Tyr phosphatase activity of EYA2 with IC50 of 3.1 uM (Eya2 ED), but not other Eya family members. |
| PC-72451 |
NCGC00378430
SIX1-EYA2 inhibitor
|
NCGC00378430 (Compound 8430) is a novel small molecule compound that reduces the SIX1/EYA2 interaction in vitro with IC50 of 52 uM in the Alphascreen assay. |
| PC-72447 |
SBI-581
TAO3 inhibitor
|
SBI-581 (SBI 581) is a potent, selective inhibitor of serine-threonine kinase TAO3 with IC50 of 42 nM, an STE20-like kinase of the GCK subfamily. |
| PC-72445 |
VLX600
Iron chelator, OXPHOS inhibitor
|
VLX600 (VLX-600) is a small molecule iron chelator and mitochondrial oxidative phosphorylation (OXPHOS) inhibitor, targets quiescent tumor cells and to inhibit mitochondrial respiration. |
| PC-72443 |
ONC212
GPR132 activator, ClpP activator
|
ONC212 (ONC-212) is a potent anti-cancer small molecule, activator of an orphan GPCR GPR132 and Gαq signaling, also is a potent activator of ClpP activator with EC50 of 131 nM. |
| PC-72440 |
AQX-435
SHIP1 activator
|
AQX-435 (AQX435) is a novel small molecule SHIP1 activator, inhibits anti-IgM-induced PI3K-mediated signaling, including induction of AKT phosphorylation and MYC expression, without effects on upstream SYK phosphorylation. |
| PC-72433 |
GRP-60367
RABV entry inhibitor
|
GRP-60367 (GRP60367) is a first-in-class, potent and specific, direct-acting rabies virus (RABV) inhibitor with EC50 of 2-52 nM on different host cell lines, inhibits entry of a subset of RABV strains. |
| PC-72408 |
SACLAC
Acid ceramidase inhibitor
|
SACLAC is an α-chloroamide ceramide analog that binds irreversibly to acid ceramidase (ASAH1), significantly reduces the viability of AML cells (EC50=3 uM) across 30 human AML cell lines. |
| PC-72399 |
Pannexin-1 inhibitor 15b
Pannexin-1 inhibitor
|
Panx-1 blocker 15b is a large-pore channel pannexin 1 (Panx1) inhibitor with IC50 of 0.8 uM. |
