Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : PAX inhibitor BG1
CAS No.: 951536-07-5
Catalog No.: PC-72554Not For Human Use, Lab Use Only.
PAX inhibitor BG1 (PAX-IN-BG1) is a small molecule inhibitor that attenuate Pax-2 transactivation ability with IC50 of 1.5 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $298 | In stock | |
| 10 mg | $458 | In stock | |
| 25 mg | Get quote | ||
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
PAX inhibitor BG1 (PAX-IN-BG1) is a small molecule inhibitor that attenuate Pax-2 transactivation ability with IC50 of 1.5 uM.
BG1 also shows ability to inhibit Pax5 and Pax8 activation of the PRS4-Luc reporter assays.
BG1 inhibits Pax2-positive cancer cell growth and target gene expression but has little effect on Pax2-negative cells.
BG1 prevent Pax protein interactions with the histone H3K4 methylation complex at Pax target genes (Cdh6) in renal cells.
| M.Wt | 336.443 | |
| Formula | C19H24N6 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
7-(4-(2,5-dimethylphenyl)piperazin-1-yl)-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine |
|
1. Shayna T J Bradford, et al. Cell Chem Biol. 2021 Nov 18;S2451-9456(21)00480-3.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
