Catalog No.: PC-72551Not For Human Use, Lab Use Only.
CTPS-IN-T35 is a potent, small molecule inhibitor of CTPS (cytidine triphosphate synthase) with IC50 of 4.7/25.7 nM against CTPS1/2 in RapdFire MS assays.
CTPS-IN-T35 is a potent, small molecule inhibitor of CTPS (cytidine triphosphate synthase) with IC50 of 4.7/25.7 nM against CTPS1/2 in RapdFire MS assays.
CTPS-IN-T35 inhibited lymphocyte proliferation (Jurkat cells IC50=6 nM, human/mouse T-Cells IC50=24/63.5 nM) by preventing expansion of CTP pools via de novo synthesis.
